Unusual illudin-type sesquiterpenoids from cultures of Agrocybe salicacola

doi:10.1007/s13659-011-0018-4

Natural Products and Bioprospecting ›› 2011, Vol. 1 ›› Issue (2): 87-92.DOI: 10.1007/s13659-011-0018-4

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Unusual illudin-type sesquiterpenoids from cultures of Agrocybe salicacola

Liang-Yan LIU^a,b, Ling ZHANG^a, Tao FENG^a, Zheng-Hui LI^a, Ze-Jun DONG^a, Xing-Yao LI^a,b, Jia SU^a,b, Yan LI^a, Ji-Kai LIU^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100039, China

Received:2011-09-19 Revised:2011-10-26 Online:2017-11-24 Published:2011-04-24
Supported by:
This project was supported by the National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Sciences Foundation of China(30830113), and MOST(2009ZX09501-029).

Unusual illudin-type sesquiterpenoids from cultures of Agrocybe salicacola

Liang-Yan LIU^a,b, Ling ZHANG^a, Tao FENG^a, Zheng-Hui LI^a, Ze-Jun DONG^a, Xing-Yao LI^a,b, Jia SU^a,b, Yan LI^a, Ji-Kai LIU^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100039, China

通讯作者: Ji-Kai LIU,E-mail:jkliu@mail.kib.ac.cn
基金资助:
This project was supported by the National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Sciences Foundation of China(30830113), and MOST(2009ZX09501-029).

Abstract

Abstract: Seven new illudin-type sesquiterpenoids, agrocybins A-G(1-7), along with three known analogues(8-10), have been isolated from the culture broth of the fungus Agrocybe salicacola. Their structures were elucidated on the basis of extensive spectroscopic data analysis and comparison with data reported in the literature. The relative stereoconfigurations of 1 and 6 were elucidated by the X-ray crystallographic diffraction analysis. Compound 1 was highly cyclized containing seven chiral carbons which arranged compactly in six rings.

Key words: Agrocybe salicacola, sesquiterpenoid, agrocybin, stereoconfiguration, X-ray

摘要： Seven new illudin-type sesquiterpenoids, agrocybins A-G(1-7), along with three known analogues(8-10), have been isolated from the culture broth of the fungus Agrocybe salicacola. Their structures were elucidated on the basis of extensive spectroscopic data analysis and comparison with data reported in the literature. The relative stereoconfigurations of 1 and 6 were elucidated by the X-ray crystallographic diffraction analysis. Compound 1 was highly cyclized containing seven chiral carbons which arranged compactly in six rings.

关键词: Agrocybe salicacola, sesquiterpenoid, agrocybin, stereoconfiguration, X-ray

Liang-Yan LIU, Ling ZHANG, Tao FENG, Zheng-Hui LI, Ze-Jun DONG, Xing-Yao LI, Jia SU, Yan LI, Ji-Kai LIU. Unusual illudin-type sesquiterpenoids from cultures of Agrocybe salicacola[J]. Natural Products and Bioprospecting, 2011, 1(2): 87-92.

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Unusual illudin-type sesquiterpenoids from cultures of Agrocybe salicacola

Unusual illudin-type sesquiterpenoids from cultures of Agrocybe salicacola

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