Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

doi:10.1007/s13659-019-0199-9

Natural Products and Bioprospecting ›› 2019, Vol. 9 ›› Issue (2): 145-148.DOI: 10.1007/s13659-019-0199-9

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Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Jun-Li Yang, Lei-Lei Liu, Yan-Ping Shi

CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China

Received:2019-01-04 Revised:2019-02-20 Online:2019-04-04 Published:2019-04-24
Contact: Yan-Ping Shi
Supported by:
This work was financially supported by National Natural Science Foundation of China (Nos.81673325,81711540311,and 21705156),the International Partnership Program of CAS (No.153631KYSB20160004),Gansu Province Key International S&T Cooperation Project (No.18YF1WA127),and CAS Pioneer Hundred Talents Prog

Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Jun-Li Yang, Lei-Lei Liu, Yan-Ping Shi

CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China

通讯作者: Yan-Ping Shi
基金资助:
This work was financially supported by National Natural Science Foundation of China (Nos.81673325,81711540311,and 21705156),the International Partnership Program of CAS (No.153631KYSB20160004),Gansu Province Key International S&T Cooperation Project (No.18YF1WA127),and CAS Pioneer Hundred Talents Prog

Abstract

Abstract: The flowers of Chrysanthemum indicum,i.e.Ye-ju-hua recorded in the Chinese Pharmacopoeia,has been widely used in China as an important heat-clearing and detoxifying herb for the treatment of inflammation,headache,and vertigo.A phytochemical investigation of this herb has led to the isolation of two new eudesmane sesquiterpenoids,7-epi-eudesm-4(15),11(13)-diene-1β,3β-diol (1) and 7-epi-1β-hydroxy-β-eudesmol (2).The molecular structures of these new sesquiterpenoids were established based on the comprehensive spectroscopic analyses,including NMR,MS,and IR,and comparing with the literatures.

Key words: Chrysanthemum indicum, Sesquiterpenoids, Eudesmane

摘要： The flowers of Chrysanthemum indicum,i.e.Ye-ju-hua recorded in the Chinese Pharmacopoeia,has been widely used in China as an important heat-clearing and detoxifying herb for the treatment of inflammation,headache,and vertigo.A phytochemical investigation of this herb has led to the isolation of two new eudesmane sesquiterpenoids,7-epi-eudesm-4(15),11(13)-diene-1β,3β-diol (1) and 7-epi-1β-hydroxy-β-eudesmol (2).The molecular structures of these new sesquiterpenoids were established based on the comprehensive spectroscopic analyses,including NMR,MS,and IR,and comparing with the literatures.

关键词: Chrysanthemum indicum, Sesquiterpenoids, Eudesmane

Jun-Li Yang, Lei-Lei Liu, Yan-Ping Shi. Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum[J]. Natural Products and Bioprospecting, 2019, 9(2): 145-148.

Jun-Li Yang, Lei-Lei Liu, Yan-Ping Shi. Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum[J]. 应用天然产物, 2019, 9(2): 145-148.

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Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

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