Furan Derivatives and Polyketides from the Fungus Irpex lacteus

doi:10.1007/s13659-020-00282-w

应用天然产物 ›› 2021, Vol. 11 ›› Issue (2): 215-222.DOI: 10.1007/s13659-020-00282-w

• ORIGINAL ARTICLES • 上一篇下一篇

Furan Derivatives and Polyketides from the Fungus Irpex lacteus

Meng Wang¹, Zheng-Hui Li¹, Masahiko Isaka², Ji-Kai Liu¹, Tao Feng¹

1 School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, People's Republic of China;
2 National Center for Genetic Engineering and Biotechnology(BIOTEC), 113 Thailand Science Park, Pathumthani 12120, Thailand

收稿日期:2020-10-04 修回日期:2020-10-31 出版日期:2021-04-24 发布日期:2021-04-07
通讯作者: Tao Feng
基金资助:
This work was financially supported by the joint research project from the National Natural Science Foundation of China (Grant No. 21961142008) and Thailand Research Fund (Grant No. DBG6280008). The authors thank Analytical & Measuring Centre, South-Central University for Nationalities for the spectra measurements.

Furan Derivatives and Polyketides from the Fungus Irpex lacteus

Meng Wang¹, Zheng-Hui Li¹, Masahiko Isaka², Ji-Kai Liu¹, Tao Feng¹

1 School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, People's Republic of China;
2 National Center for Genetic Engineering and Biotechnology(BIOTEC), 113 Thailand Science Park, Pathumthani 12120, Thailand

Received:2020-10-04 Revised:2020-10-31 Online:2021-04-24 Published:2021-04-07
Contact: Tao Feng
Supported by:
This work was financially supported by the joint research project from the National Natural Science Foundation of China (Grant No. 21961142008) and Thailand Research Fund (Grant No. DBG6280008). The authors thank Analytical & Measuring Centre, South-Central University for Nationalities for the spectra measurements.

摘要/Abstract

摘要： Eight new furan derivatives, irpexins A-H (1-8), two new polyketides, irpexins I and J (9 and 10), together with nine known compounds were isolated from the fermentation of Irpex lacteus. The structures and absolute configurations were elucidated on the basis of extensive spectroscopic methods and Mosher ester reaction. All compounds shows no cytotoxicity to human MCF-7 and Hela cancer cell lines at the concentration of 10 μM.

关键词: Irpex lacteus, Furan derivatives, Polyketides

Abstract: Eight new furan derivatives, irpexins A-H (1-8), two new polyketides, irpexins I and J (9 and 10), together with nine known compounds were isolated from the fermentation of Irpex lacteus. The structures and absolute configurations were elucidated on the basis of extensive spectroscopic methods and Mosher ester reaction. All compounds shows no cytotoxicity to human MCF-7 and Hela cancer cell lines at the concentration of 10 μM.

Key words: Irpex lacteus, Furan derivatives, Polyketides

Meng Wang, Zheng-Hui Li, Masahiko Isaka, Ji-Kai Liu, Tao Feng. Furan Derivatives and Polyketides from the Fungus Irpex lacteus[J]. 应用天然产物, 2021, 11(2): 215-222.

Meng Wang, Zheng-Hui Li, Masahiko Isaka, Ji-Kai Liu, Tao Feng. Furan Derivatives and Polyketides from the Fungus Irpex lacteus[J]. Natural Products and Bioprospecting, 2021, 11(2): 215-222.

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Furan Derivatives and Polyketides from the Fungus Irpex lacteus

Furan Derivatives and Polyketides from the Fungus Irpex lacteus

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