Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66

doi:10.1007/s13659-020-00248-y

Natural Products and Bioprospecting ›› 2020, Vol. 10 ›› Issue (4): 201-207.DOI: 10.1007/s13659-020-00248-y

• ORIGINAL ARTICLES • Previous Articles Next Articles

Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66

Xiao-Zheng Su^1,2,3, Jian-Wei Tang^1,2, Kun Hu^1,2, Xiao-Nian Li^1,2, Han-Dong Sun^1,2, Pema-Tenzin Puno^1,2

1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
3 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China

Received:2020-04-20 Revised:2020-05-31 Online:2020-08-19 Published:2020-08-24
Contact: Pema-Tenzin Puno
Supported by:
This project was supported financially by the National Natural Science Foundation of China (No. 81874298), the CAS "Light of West China" program (Pema-Tenzin Puno), and the Yunnan Science Fund for Distinguished Young Scholars (2019FJ002).

Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66

Xiao-Zheng Su^1,2,3, Jian-Wei Tang^1,2, Kun Hu^1,2, Xiao-Nian Li^1,2, Han-Dong Sun^1,2, Pema-Tenzin Puno^1,2

1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
3 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China

通讯作者: Pema-Tenzin Puno
基金资助:
This project was supported financially by the National Natural Science Foundation of China (No. 81874298), the CAS "Light of West China" program (Pema-Tenzin Puno), and the Yunnan Science Fund for Distinguished Young Scholars (2019FJ002).

Abstract

Abstract: Arthrinins E-G (1-3), three new sesquiterpenoids possessing non-isoprenoid botryane skeleton, were isolated from the fermentation of an endophytic fungus named Arthrinium sp. HS66 which colonized in the stems of Isodon xerophilus. Their structures were determined by extensive spectroscopic methods. Furthermore, the structure of 1 was unambiguously confirmed by X-ray diffraction, while those of 2 and 3 were verified through quantum chemical calculation of NMR data and ECD spectra.

Key words: Isodon xerophilus, Endophytic fungus, Arthrinium, Botryane sesquiterpenoid, Quantum chemical calculation

摘要： Arthrinins E-G (1-3), three new sesquiterpenoids possessing non-isoprenoid botryane skeleton, were isolated from the fermentation of an endophytic fungus named Arthrinium sp. HS66 which colonized in the stems of Isodon xerophilus. Their structures were determined by extensive spectroscopic methods. Furthermore, the structure of 1 was unambiguously confirmed by X-ray diffraction, while those of 2 and 3 were verified through quantum chemical calculation of NMR data and ECD spectra.

关键词: Isodon xerophilus, Endophytic fungus, Arthrinium, Botryane sesquiterpenoid, Quantum chemical calculation

Xiao-Zheng Su, Jian-Wei Tang, Kun Hu, Xiao-Nian Li, Han-Dong Sun, Pema-Tenzin Puno. Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66[J]. Natural Products and Bioprospecting, 2020, 10(4): 201-207.

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Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66

Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66

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