Sesquiterpenoids from the Rhizomes of Homalomena occulta

doi:10.1007/s13659-016-0104-8

Natural Products and Bioprospecting ›› 2016, Vol. 6 ›› Issue (4): 211-216.DOI: 10.1007/s13659-016-0104-8

• Original article • Previous Articles Next Articles

Sesquiterpenoids from the Rhizomes of Homalomena occulta

Jun-Li Yang¹, Ya-Min Zhao¹, Yan-Ping Shi^1,2

1. Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China;
2. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China

Received:2016-05-22 Revised:2016-06-23 Online:2018-02-08 Published:2016-08-24
Supported by:
The work was financially supported by the National Nature Science Foundation of China (Nos.21375136 and 21575150),and the scientific research project of Central Asia Drug Discovery and Development Centre of Chinese Academy of Sciences (No.CAM201404) and the CAS Pioneer Hundred Talents Program

Sesquiterpenoids from the Rhizomes of Homalomena occulta

Jun-Li Yang¹, Ya-Min Zhao¹, Yan-Ping Shi^1,2

1. Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, People's Republic of China;
2. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China

通讯作者: Yan-Ping Shi,e-mail:shiyp@licp.cas.cn
基金资助:
The work was financially supported by the National Nature Science Foundation of China (Nos.21375136 and 21575150),and the scientific research project of Central Asia Drug Discovery and Development Centre of Chinese Academy of Sciences (No.CAM201404) and the CAS Pioneer Hundred Talents Program

Abstract

Abstract: Naturally occurring oplopanane sesquiterpenoids are rarely reported. A phytochemical investigation on the rhizomes of Homalomena occulta (Lours) has resulted in the discovery of six oplopanane sesquiterpenoids (1-6), including four new (1-4) and one 3,5-seco-oplopanane (6), together with three previously reported sesquiterpenoids (7-9). In addition three new oplopananes (2a-4a) were also obtained by chemical transformation. All structures of these sesquiterpenoids were established based on the comprehensive spectroscopic analyses, including NMR, MS, and IR, and comparing with the literatures.

Key words: Homalomena occulta, Sesquiterpenoids, Oplopananes

摘要： Naturally occurring oplopanane sesquiterpenoids are rarely reported. A phytochemical investigation on the rhizomes of Homalomena occulta (Lours) has resulted in the discovery of six oplopanane sesquiterpenoids (1-6), including four new (1-4) and one 3,5-seco-oplopanane (6), together with three previously reported sesquiterpenoids (7-9). In addition three new oplopananes (2a-4a) were also obtained by chemical transformation. All structures of these sesquiterpenoids were established based on the comprehensive spectroscopic analyses, including NMR, MS, and IR, and comparing with the literatures.

关键词: Homalomena occulta, Sesquiterpenoids, Oplopananes

Jun-Li Yang, Ya-Min Zhao, Yan-Ping Shi. Sesquiterpenoids from the Rhizomes of Homalomena occulta[J]. Natural Products and Bioprospecting, 2016, 6(4): 211-216.

Jun-Li Yang, Ya-Min Zhao, Yan-Ping Shi. Sesquiterpenoids from the Rhizomes of Homalomena occulta[J]. 应用天然产物, 2016, 6(4): 211-216.

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Sesquiterpenoids from the Rhizomes of Homalomena occulta

Sesquiterpenoids from the Rhizomes of Homalomena occulta

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