Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla

doi:10.1007/s13659-016-0102-x

Natural Products and Bioprospecting ›› 2016, Vol. 6 ›› Issue (4): 205-210.DOI: 10.1007/s13659-016-0102-x

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Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla

Ling-Yu Jin^1,2, Ting-Xiang Lu²², . Xu-Jie Qin², Wei Ni², Huan Yan³, Yu Chen³, Hui Liu¹, Hong-Ping He²

1. College of Pharmacy and Chemistry, Dali University, Dali 671000, China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
3. University of Chinese Academy of Sciences, Beijing 100049, China

Received:2016-04-15 Revised:2016-05-13 Online:2018-02-08 Published:2016-08-24
Supported by:
This work is funded by the National Natural Science Funding of China (Grand No.31570363);the Key Research Program of the Chinese Academy of Sciences (Grand No.KSZDEW-Z-004-03-4),and the Natural Science Foundation of Yunnan Province (Grand No.2015FA031)

Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla

Ling-Yu Jin^1,2, Ting-Xiang Lu²², . Xu-Jie Qin², Wei Ni², Huan Yan³, Yu Chen³, Hui Liu¹, Hong-Ping He²

1. College of Pharmacy and Chemistry, Dali University, Dali 671000, China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
3. University of Chinese Academy of Sciences, Beijing 100049, China

通讯作者: Hong-Ping He,e-mail:95431111@qq.com;Hai-Yang Liu,e-mail:haiyangliu@mail.kib.ac.cn
基金资助:
This work is funded by the National Natural Science Funding of China (Grand No.31570363);the Key Research Program of the Chinese Academy of Sciences (Grand No.KSZDEW-Z-004-03-4),and the Natural Science Foundation of Yunnan Province (Grand No.2015FA031)

Abstract

Abstract: Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. In addition, the cytotoxicity of the two new saponins was tested.

Key words: Paris polyphylla var. stenophylla, Liliaceae, Spirostanol saponins, Paristenoside A, Paristenoside B

摘要： Phytochemical investigation of the rhizomes of Paris polyphylla var. stenophylla led to the isolation of two new highly oxygenated spirostanol saponins, named paristenosides A (1) and B (2), together with seven known compounds. Their structures were established mainly on the base of NMR spectroscopic techniques and mass spectrometry, as well as chemical methods. In addition, the cytotoxicity of the two new saponins was tested.

关键词: Paris polyphylla var. stenophylla, Liliaceae, Spirostanol saponins, Paristenoside A, Paristenoside B

Ling-Yu Jin, Ting-Xiang Lu,. Xu-Jie Qin, Wei Ni, Huan Yan, Yu Chen, Hui Liu, Hong-Ping He, Hai-Yang Liu. Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla[J]. Natural Products and Bioprospecting, 2016, 6(4): 205-210.

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Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla

Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla

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