Abstract: Phytochemicalinvestigationonthewholeplantsof Ypsilandrayunnanensiswascarriedoutforthefirsttimeandledtothe isolation of five new cholestanol glycosides, ypsiyunnosides A-E (1-5), and one known analogue. Their structures were determined mainly by detailed spectroscopic analysis, including extensive 1D and 2D NMR, MS and UV, as well as chemical methods. Among them, compound 1 possessed a rare 6/6/6/5/5 fused-rings cholestanol sketelon, which was identified as (23R,25R)-3β,16α,26-triol- 16,23-cyclocholest-5,17(20)-dien-22-one. Their induced platelet aggregation activities and cytotoxicities were evaluated.

Key words: Ypsilandra yunnanensis, Liliaceae, Cholestane glycoside, Ypsiyunnosides A-E

摘要： Phytochemicalinvestigationonthewholeplantsof Ypsilandrayunnanensiswascarriedoutforthefirsttimeandledtothe isolation of five new cholestanol glycosides, ypsiyunnosides A-E (1-5), and one known analogue. Their structures were determined mainly by detailed spectroscopic analysis, including extensive 1D and 2D NMR, MS and UV, as well as chemical methods. Among them, compound 1 possessed a rare 6/6/6/5/5 fused-rings cholestanol sketelon, which was identified as (23R,25R)-3β,16α,26-triol- 16,23-cyclocholest-5,17(20)-dien-22-one. Their induced platelet aggregation activities and cytotoxicities were evaluated.

关键词: Ypsilandra yunnanensis, Liliaceae, Cholestane glycoside, Ypsiyunnosides A-E