Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

doi:10.1007/s13659-016-0093-7

Natural Products and Bioprospecting ›› 2016, Vol. 6 ›› Issue (3): 149-154.DOI: 10.1007/s13659-016-0093-7

• Original article • Next Articles

Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

Ling Ni^1,2, Xiu-Hong Zhong^1,2, Jie Cai³, Mei-Fen Bao^1,2, Bing-Jie Zhang¹, Jing Wu^1,2, Xiang-Hai Cai¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. University of Chinese Academy of Sciences, Beijing 100039, People's Republic of China;
3. Germplasm Bank of Wild Species in Southwest China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China

Received:2016-01-22 Revised:2016-03-13 Online:2018-02-08 Published:2016-06-24
Supported by:
This project was financially supported by the Young Academic and Technical Leader Raising Foundation of Yunnan Province (No.2010CI049)

Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

Ling Ni^1,2, Xiu-Hong Zhong^1,2, Jie Cai³, Mei-Fen Bao^1,2, Bing-Jie Zhang¹, Jing Wu^1,2, Xiang-Hai Cai¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. University of Chinese Academy of Sciences, Beijing 100039, People's Republic of China;
3. Germplasm Bank of Wild Species in Southwest China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China

通讯作者: Xiang-Hai Cai,e-mail:xhcai@mail.kib.ac.cn
基金资助:
This project was financially supported by the Young Academic and Technical Leader Raising Foundation of Yunnan Province (No.2010CI049)

Abstract

Abstract: Five new alkaloids (1-5) were isolated from the leaves and twigs of Cephalotaxus lanceolata and C. fortunei var. alpina along with 24 known alkaloids. The new structures were elucidated based on spectroscopic data including 1D and 2D NMR, FTIR, UV and MS. These new alkaloids showed no cytotoxicity to HeLa, SGC-7901 gastric cancer, and A-549 lung cancer cell lines.

Key words: Cephalotaxus, Alkaloids, Cytotoxicity

摘要： Five new alkaloids (1-5) were isolated from the leaves and twigs of Cephalotaxus lanceolata and C. fortunei var. alpina along with 24 known alkaloids. The new structures were elucidated based on spectroscopic data including 1D and 2D NMR, FTIR, UV and MS. These new alkaloids showed no cytotoxicity to HeLa, SGC-7901 gastric cancer, and A-549 lung cancer cell lines.

关键词: Cephalotaxus, Alkaloids, Cytotoxicity

Ling Ni, Xiu-Hong Zhong, Jie Cai, Mei-Fen Bao, Bing-Jie Zhang, Jing Wu, Xiang-Hai Cai. Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina[J]. Natural Products and Bioprospecting, 2016, 6(3): 149-154.

Ling Ni, Xiu-Hong Zhong, Jie Cai, Mei-Fen Bao, Bing-Jie Zhang, Jing Wu, Xiang-Hai Cai. Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina[J]. 应用天然产物, 2016, 6(3): 149-154.

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Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

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