Indole Glycosides from Aqueous Fraction of Strychnos nitida

doi:10.1007/s13659-016-0112-8

应用天然产物 ›› 2016, Vol. 6 ›› Issue (6): 285-290.DOI: 10.1007/s13659-016-0112-8

• Original article • 上一篇下一篇

Indole Glycosides from Aqueous Fraction of Strychnos nitida

Bei Wang^1,2, Zhi Dai³, Lu Liu^1,2, Xin Wei^1,2, Pei-Feng Zhu², Hao-Fei Yu^1,2, Ya-Ping Liu^1,4, Xiao-Dong Luo^1,4

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming 650201, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China;
3. Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of sciences, Kunming 650223, Yunnan, China;
4. Yunnan Key Laboratory of Natural Medicinal Chemistry, Chinese Academy of Sciences, Kunming 650201, China

收稿日期:2016-10-08 修回日期:2016-10-18 出版日期:2016-12-24 发布日期:2018-01-31
通讯作者: Ya-Ping Liu,e-mail:liuyaping@mail.kib.ac.cn;Xiao-Dong Luo,e-mail:xdluo@mail.kib.ac.cn
基金资助:
This project was financially supported by the National Natural Science Foundation of China (81225024);We also thank the analytical group of the Laboratory of Phytochemistry,Kunming Institute of Botany for spectral measurements

Indole Glycosides from Aqueous Fraction of Strychnos nitida

Bei Wang^1,2, Zhi Dai³, Lu Liu^1,2, Xin Wei^1,2, Pei-Feng Zhu², Hao-Fei Yu^1,2, Ya-Ping Liu^1,4, Xiao-Dong Luo^1,4

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming 650201, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China;
3. Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of sciences, Kunming 650223, Yunnan, China;
4. Yunnan Key Laboratory of Natural Medicinal Chemistry, Chinese Academy of Sciences, Kunming 650201, China

Received:2016-10-08 Revised:2016-10-18 Online:2016-12-24 Published:2018-01-31
Supported by:
This project was financially supported by the National Natural Science Foundation of China (81225024);We also thank the analytical group of the Laboratory of Phytochemistry,Kunming Institute of Botany for spectral measurements

摘要/Abstract

摘要： Three new indole glycosides 22-deoxystrictosamide (1), 22-deoxystrictosamide N^b-oxide (2) and vincosamide 2'-O-β-D-xylopyranoside-11-O-β-D-glucopyranoside (3), together with four known analogues were isolated from aqueous fraction of Strychnos nitida. Their structures were elucidated on the basis of extensive analysis of spectroscopic data. All the alkaloids were tested for their cytotoxic activity, but they did not show any exciting result.

关键词: Strychnos nitida, Indole glycosides, Alkaloids

Abstract: Three new indole glycosides 22-deoxystrictosamide (1), 22-deoxystrictosamide N^b-oxide (2) and vincosamide 2'-O-β-D-xylopyranoside-11-O-β-D-glucopyranoside (3), together with four known analogues were isolated from aqueous fraction of Strychnos nitida. Their structures were elucidated on the basis of extensive analysis of spectroscopic data. All the alkaloids were tested for their cytotoxic activity, but they did not show any exciting result.

Key words: Strychnos nitida, Indole glycosides, Alkaloids

Bei Wang, Zhi Dai, Lu Liu, Xin Wei, Pei-Feng Zhu, Hao-Fei Yu, Ya-Ping Liu, Xiao-Dong Luo. Indole Glycosides from Aqueous Fraction of Strychnos nitida[J]. 应用天然产物, 2016, 6(6): 285-290.

Bei Wang, Zhi Dai, Lu Liu, Xin Wei, Pei-Feng Zhu, Hao-Fei Yu, Ya-Ping Liu, Xiao-Dong Luo. Indole Glycosides from Aqueous Fraction of Strychnos nitida[J]. Natural Products and Bioprospecting, 2016, 6(6): 285-290.

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Indole Glycosides from Aqueous Fraction of Strychnos nitida

Indole Glycosides from Aqueous Fraction of Strychnos nitida

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