Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum

doi:10.1007/s13659-016-0111-9

应用天然产物 ›› 2016, Vol. 6 ›› Issue (6): 279-284.DOI: 10.1007/s13659-016-0111-9

• Original article • 上一篇下一篇

Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum

Jin-Tang Cheng^1,3, Zhi-Jun Zhang¹, Xiao-Nian Li¹, Li-Yan Peng¹, Huai-Rong Luo¹, Xing-De Wu¹, Qin-Shi Zhao^1,2

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, People's Republic of China

收稿日期:2016-09-02 修回日期:2016-10-10 出版日期:2016-12-24 发布日期:2018-01-31
通讯作者: Xing-De Wu,e-mail:wuxingde@mail.kib.ac.cn;Qin-Shi Zhao,e-mail:qinshizhao@mail.kib.ac.cn
基金资助:
This work was financially supported by the NSFC-Joint Foundation of Yunnan Province (No.U1502223);the National Natural Science Foundation of China (No.21402212);the Science and Technology Program of Yunnan Province (No.2015FB173),and the CAS "Light of West China" Program and Youth Innovation Promotion Association CAS (X.-D.Wu)

Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum

Jin-Tang Cheng^1,3, Zhi-Jun Zhang¹, Xiao-Nian Li¹, Li-Yan Peng¹, Huai-Rong Luo¹, Xing-De Wu¹, Qin-Shi Zhao^1,2

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, People's Republic of China

Received:2016-09-02 Revised:2016-10-10 Online:2016-12-24 Published:2018-01-31
Supported by:
This work was financially supported by the NSFC-Joint Foundation of Yunnan Province (No.U1502223);the National Natural Science Foundation of China (No.21402212);the Science and Technology Program of Yunnan Province (No.2015FB173),and the CAS "Light of West China" Program and Youth Innovation Promotion Association CAS (X.-D.Wu)

摘要/Abstract

摘要： Two rare lyconadin-type Lycopodium alkaloids, lyconadins G (1) and H (2), together with four known ones (3-6), were isolated from Lycopodium complanatum. The structures were determined on the basis of their spectroscopic analyses, and the absolute configuration of 1 was established by an X-ray crystallographic analysis. It is the first time to establish the absolute configuration of lyconadin-type Lycopodium alkaloid by an X-ray diffraction experiment. In addition, these findings may provide more information for the biosynthesis of lyconadins.

关键词: Lycopodium alkaloids, Lycopodium complanatum, Lyconad

Abstract: Two rare lyconadin-type Lycopodium alkaloids, lyconadins G (1) and H (2), together with four known ones (3-6), were isolated from Lycopodium complanatum. The structures were determined on the basis of their spectroscopic analyses, and the absolute configuration of 1 was established by an X-ray crystallographic analysis. It is the first time to establish the absolute configuration of lyconadin-type Lycopodium alkaloid by an X-ray diffraction experiment. In addition, these findings may provide more information for the biosynthesis of lyconadins.

Key words: Lycopodium alkaloids, Lycopodium complanatum, Lyconad

Jin-Tang Cheng, Zhi-Jun Zhang, Xiao-Nian Li, Li-Yan Peng, Huai-Rong Luo, Xing-De Wu, Qin-Shi Zhao. Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum[J]. 应用天然产物, 2016, 6(6): 279-284.

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Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum

Lyconadins G and H, Two Rare Lyconadin-Type Lycopodium Alkaloids from Lycopodium complanatum

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