应用天然产物 ›› 2020, Vol. 10 ›› Issue (1): 45-49.DOI: 10.1007/s13659-020-00233-5
Xin-Yu Jia1, Yong-Mei Wu2, Jing-Ya Li2, Chun Lei1, Ai-Jun Hou1
收稿日期:2020-01-14
修回日期:2020-02-06
出版日期:2020-02-24
发布日期:2020-02-29
通讯作者:
Chun Lei, Ai-Jun Hou
基金资助:Xin-Yu Jia1, Yong-Mei Wu2, Jing-Ya Li2, Chun Lei1, Ai-Jun Hou1
Received:2020-01-14
Revised:2020-02-06
Online:2020-02-24
Published:2020-02-29
Contact:
Chun Lei, Ai-Jun Hou
Supported by:摘要： Four new alkaloids, ficuhismines A-D (1-4), together with three known ones, were isolated from Ficus hispida. Their structures were elucidated by spectroscopic analysis and chemical method. The new compounds represent the first amine alkaloids with a rhamnosyl moiety (1-2) or with a N-oxide motif (2-4) from the genus Ficus. Compound 2 showed potent inhibitory effect in nuclear factor-κB (NF-κB) pathway luciferase assay with IC50 value of 0.52±0.11 μM.
Xin-Yu Jia, Yong-Mei Wu, Jing-Ya Li, Chun Lei, Ai-Jun Hou. Alkaloid Constituents of Ficus hispida and Their Antiinflammatory Activity[J]. 应用天然产物, 2020, 10(1): 45-49.
Xin-Yu Jia, Yong-Mei Wu, Jing-Ya Li, Chun Lei, Ai-Jun Hou. Alkaloid Constituents of Ficus hispida and Their Antiinflammatory Activity[J]. Natural Products and Bioprospecting, 2020, 10(1): 45-49.
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