New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica

doi:10.1007/s13659-018-0181-y

Natural Products and Bioprospecting ›› 2018, Vol. 8 ›› Issue (6): 413-418.DOI: 10.1007/s13659-018-0181-y

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New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica

Xia Wang^1,2, Xing-Rong Peng¹, Jing Lu^1,2, Gui-Lin Hu^1,2, Ming-Hua Qiu^1,2

1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2 University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China

Received:2018-04-13 Revised:2018-07-09 Online:2018-11-21 Published:2018-12-24
Contact: Ming-Hua Qiu
Supported by:
This study was supported financially by the National Natural Science Foundation of China, China (No. 31670364), Project of Key New Productions of Yunnan Province, China (No. 2015BB002), the STS Programme of Chinese Academy of Sciences, China (KFJ-SW-STS-143-8), Special Fund Project of Pu'er municipal government, China (2017), as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China, China (P2015-ZZ09).

New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica

Xia Wang^1,2, Xing-Rong Peng¹, Jing Lu^1,2, Gui-Lin Hu^1,2, Ming-Hua Qiu^1,2

1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2 University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China

通讯作者: Ming-Hua Qiu
基金资助:
This study was supported financially by the National Natural Science Foundation of China, China (No. 31670364), Project of Key New Productions of Yunnan Province, China (No. 2015BB002), the STS Programme of Chinese Academy of Sciences, China (KFJ-SW-STS-143-8), Special Fund Project of Pu'er municipal government, China (2017), as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China, China (P2015-ZZ09).

Abstract

Abstract: In present study, four new dammarane-type triterpenoids, namely caffruones A-D (1-4), were isolated from the cherries of Coffea arabica. Their structures were elucidated by extensive spectroscopic analysis including 1D, 2D NMR (HSQC, HMBC, ¹H-¹H COSY, and ROESY), HRMS and IR spectra. This is the first time that tetracyclic triterpenes have been reported in genus Coffea.

Key words: Coffea arabica, Cherries, Triterpenoids, Structural elucidation

摘要： In present study, four new dammarane-type triterpenoids, namely caffruones A-D (1-4), were isolated from the cherries of Coffea arabica. Their structures were elucidated by extensive spectroscopic analysis including 1D, 2D NMR (HSQC, HMBC, ¹H-¹H COSY, and ROESY), HRMS and IR spectra. This is the first time that tetracyclic triterpenes have been reported in genus Coffea.

关键词: Coffea arabica, Cherries, Triterpenoids, Structural elucidation

Xia Wang, Xing-Rong Peng, Jing Lu, Gui-Lin Hu, Ming-Hua Qiu. New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica[J]. Natural Products and Bioprospecting, 2018, 8(6): 413-418.

Xia Wang, Xing-Rong Peng, Jing Lu, Gui-Lin Hu, Ming-Hua Qiu. New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica[J]. 应用天然产物, 2018, 8(6): 413-418.

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New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica

New Dammarane Triterpenoids, Caffruones A-D, from the Cherries of Coffea arabica

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