The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review

doi:10.1007/s13659-019-00222-3

Natural Products and Bioprospecting ›› 2019, Vol. 9 ›› Issue (6): 357-392.DOI: 10.1007/s13659-019-00222-3

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The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review

Xiao-Rui Zhang^1,2, Joseph Sakah Kaunda^1,2, Hong-Tao Zhu¹, Dong Wang¹, Chong-Ren Yang¹, Ying-Jun Zhang^1,3

1 State Key Laboratory of Phytochemistry and Plant Resources in West China. Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China;
2 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China;
3 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China

Received:2019-07-31 Revised:2019-10-15 Online:2019-12-11 Published:2019-12-24
Contact: Ying-Jun Zhang
Supported by:
This work was supported by the Key Projects of Yunnan Science and Technology, and Yunnan Key Laboratory of Natural Medicinal Chemistry (S2017-ZZ14).

The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review

Xiao-Rui Zhang^1,2, Joseph Sakah Kaunda^1,2, Hong-Tao Zhu¹, Dong Wang¹, Chong-Ren Yang¹, Ying-Jun Zhang^1,3

1 State Key Laboratory of Phytochemistry and Plant Resources in West China. Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China;
2 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China;
3 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China

通讯作者: Ying-Jun Zhang
基金资助:
This work was supported by the Key Projects of Yunnan Science and Technology, and Yunnan Key Laboratory of Natural Medicinal Chemistry (S2017-ZZ14).

Abstract

Abstract: Terminalia Linn, a genus of mostly medium or large trees in the family Combretaceae with about 250 species in the world, is distributed mainly in southern Asia, Himalayas, Madagascar, Australia, and the tropical and subtropical regions of Africa. Many species are used widely in many traditional medicinal systems, e.g., traditional Chinese medicine, Tibetan medicine, and Indian Ayurvedic medicine practices. So far, about 39 species have been phytochemically studied, which led to the identification of 368 compounds, including terpenoids, tannins, flavonoids, phenylpropanoids, simple phenolics and so on. Some of the isolates showed various bioactivities, in vitro or in vivo, such as antitumor, anti HIV-1, antifungal, antimicrobial, antimalarial, antioxidant, diarrhea and analgesic. This review covers research articles from 1934 to 2018, retrieved from SciFinder, Wikipedia, Google Scholar, Chinese Knowledge Network and Baidu Scholar by using "Terminalia" as the search term ("all fields") with no specific time frame setting for the search. Thirty-nine important medicinal and edible Terminalia species were selected and summarized on their geographical distribution, traditional uses, phytochemistry and related pharmacological activities.

Key words: Terminalia, Combretaceae, Ethnomedicine, Traditional uses, Phytochemistry, Hydrolyzable tannins, Pharmacology

摘要： Terminalia Linn, a genus of mostly medium or large trees in the family Combretaceae with about 250 species in the world, is distributed mainly in southern Asia, Himalayas, Madagascar, Australia, and the tropical and subtropical regions of Africa. Many species are used widely in many traditional medicinal systems, e.g., traditional Chinese medicine, Tibetan medicine, and Indian Ayurvedic medicine practices. So far, about 39 species have been phytochemically studied, which led to the identification of 368 compounds, including terpenoids, tannins, flavonoids, phenylpropanoids, simple phenolics and so on. Some of the isolates showed various bioactivities, in vitro or in vivo, such as antitumor, anti HIV-1, antifungal, antimicrobial, antimalarial, antioxidant, diarrhea and analgesic. This review covers research articles from 1934 to 2018, retrieved from SciFinder, Wikipedia, Google Scholar, Chinese Knowledge Network and Baidu Scholar by using "Terminalia" as the search term ("all fields") with no specific time frame setting for the search. Thirty-nine important medicinal and edible Terminalia species were selected and summarized on their geographical distribution, traditional uses, phytochemistry and related pharmacological activities.

关键词: Terminalia, Combretaceae, Ethnomedicine, Traditional uses, Phytochemistry, Hydrolyzable tannins, Pharmacology

Xiao-Rui Zhang, Joseph Sakah Kaunda, Hong-Tao Zhu, Dong Wang, Chong-Ren Yang, Ying-Jun Zhang. The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review[J]. Natural Products and Bioprospecting, 2019, 9(6): 357-392.

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The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review

The Genus Terminalia (Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review

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