New Dimeric and seco-Abietane Diterpenoids from Salvia wardii

doi:10.1007/s13659-015-0054-6

Natural Products and Bioprospecting ›› 2015, Vol. 5 ›› Issue (2): 77-82.DOI: 10.1007/s13659-015-0054-6

• Original article • Previous Articles Next Articles

New Dimeric and seco-Abietane Diterpenoids from Salvia wardii

Qiu-Li Xiao¹, Fan Xia¹, Xing-Wei Yang², Yang Liao², Li-Xin Yang², Yu-Kun Wei³, Xian Li¹, Gang Xu²

1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming 650500, Yunnan, People's Republic of China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
3. Shanghai Chenshan Plant Science Research Center, Chinese Academy of Sciences, Beijing, People's Republic of China

Received:2015-01-26 Revised:2015-02-14 Online:2018-02-11 Published:2015-04-24
Supported by:
The work was financially supported by the foundations from NSFC(81373291), the National Science and Technology Support Program of China(2013BAI11B02), the Young Academic Leader Raising Foundation of Yunnan Province(No. 2009CI073), and the foundation from CAS to Dr. G. Xu.

New Dimeric and seco-Abietane Diterpenoids from Salvia wardii

Qiu-Li Xiao¹, Fan Xia¹, Xing-Wei Yang², Yang Liao², Li-Xin Yang², Yu-Kun Wei³, Xian Li¹, Gang Xu²

1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming 650500, Yunnan, People's Republic of China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
3. Shanghai Chenshan Plant Science Research Center, Chinese Academy of Sciences, Beijing, People's Republic of China

基金资助:
The work was financially supported by the foundations from NSFC(81373291), the National Science and Technology Support Program of China(2013BAI11B02), the Young Academic Leader Raising Foundation of Yunnan Province(No. 2009CI073), and the foundation from CAS to Dr. G. Xu.

Abstract

Abstract: Two dimeric abietane diterpenoids, salviwardins A and B(1 and 2), and a seco-abietane diterpenoid salviwardin C(3), along with five known analogues(4-8), were isolated from the roots of Salvia wardii. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested.

Key words: Salvia wardii, Dimeric abietane diterpenoids, seco-abietane

摘要： Two dimeric abietane diterpenoids, salviwardins A and B(1 and 2), and a seco-abietane diterpenoid salviwardin C(3), along with five known analogues(4-8), were isolated from the roots of Salvia wardii. The structures of these isolates were elucidated by extensive spectroscopic methods. The inhibitory activities of these isolates against five human cancer cell lines in vitro were also tested.

关键词: Salvia wardii, Dimeric abietane diterpenoids, seco-abietane

Qiu-Li Xiao, Fan Xia, Xing-Wei Yang, Yang Liao, Li-Xin Yang, Yu-Kun Wei, Xian Li, Gang Xu. New Dimeric and seco-Abietane Diterpenoids from Salvia wardii[J]. Natural Products and Bioprospecting, 2015, 5(2): 77-82.

Qiu-Li Xiao, Fan Xia, Xing-Wei Yang, Yang Liao, Li-Xin Yang, Yu-Kun Wei, Xian Li, Gang Xu. New Dimeric and seco-Abietane Diterpenoids from Salvia wardii[J]. 应用天然产物, 2015, 5(2): 77-82.

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New Dimeric and seco-Abietane Diterpenoids from Salvia wardii

New Dimeric and seco-Abietane Diterpenoids from Salvia wardii

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