A review on pharmacological and analytical aspects of diosgenin:a concise report

doi:10.1007/s13659-012-0014-3

Abstract

Abstract: Diosgenin is a steroidal sapogenin found in plants such as Dioscorea nipponoca, Solanum incanum, Solanum xanthocarpum and Trigonella foenum graecum. Diosgenin, biologically active phytochemicals have been used for the treatment of various types of disorder such as leukemia, inflammation, hypercholesterolemia and cancer. It is also able to prevent bone loss to the same extent as that of oestrogen. It is a typical initial intermediate for synthesis of steroidal compounds, oral contraceptives and sex hormones. Dioscorea, Costus and Trigonella are mainly used for the production of diosgenin. On the basis of literature survey it divulges that diosgenin has very impressive pharmacological profile and could be used as a medicine for the treatment of different types of disorders in the future. Thus, the present work aims to provide collective information in concern with its pharmacological activity and phytoanalytical techniques. This review will be beneficial to researches for the development of an alternative method for the treatment of innumerable diseases from diosgenin.

Key words: analytical techniques, cancer, diosgenin, pharmacological activity, plant source, seperation techniques

摘要： Diosgenin is a steroidal sapogenin found in plants such as Dioscorea nipponoca, Solanum incanum, Solanum xanthocarpum and Trigonella foenum graecum. Diosgenin, biologically active phytochemicals have been used for the treatment of various types of disorder such as leukemia, inflammation, hypercholesterolemia and cancer. It is also able to prevent bone loss to the same extent as that of oestrogen. It is a typical initial intermediate for synthesis of steroidal compounds, oral contraceptives and sex hormones. Dioscorea, Costus and Trigonella are mainly used for the production of diosgenin. On the basis of literature survey it divulges that diosgenin has very impressive pharmacological profile and could be used as a medicine for the treatment of different types of disorders in the future. Thus, the present work aims to provide collective information in concern with its pharmacological activity and phytoanalytical techniques. This review will be beneficial to researches for the development of an alternative method for the treatment of innumerable diseases from diosgenin.

关键词: analytical techniques, cancer, diosgenin, pharmacological activity, plant source, seperation techniques

Kanika PATEL, Manoj GADEWAR, Vijay TAHILYANI, Dinesh Kumar PATEL. A review on pharmacological and analytical aspects of diosgenin:a concise report[J]. Natural Products and Bioprospecting, 2012, 2(2): 46-52.

Kanika PATEL, Manoj GADEWAR, Vijay TAHILYANI, Dinesh Kumar PATEL. A review on pharmacological and analytical aspects of diosgenin:a concise report[J]. 应用天然产物, 2012, 2(2): 46-52.

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