Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum

doi:10.1007/s13659-012-0022-3

应用天然产物 ›› 2013, Vol. 3 ›› Issue (2): 38-42.DOI: 10.1007/s13659-012-0022-3

• Regular Article • 下一篇

Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum

Ming-Ming LI, Kou WANG, Juan HE, Li-Yan PENG, Xuan-Qin CHEN, Xiao CHENG, Qin-Shi ZHAO

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

收稿日期:2012-03-13 修回日期:2013-02-24 出版日期:2013-04-24 发布日期:2018-02-11
通讯作者: Qin-Shi ZHAO,E-mail:qinshizhao@mail.kib.ac.cn
基金资助:
This work was financially supported by the National Basic Research Program of China (973 Program Nos. 2009CB522303 and 2011CB915503), the National Natural Science Foundation of China (Nos. 90813004 and U0932602), the projects from Chinese Academy of sciences (Nos. 2009311211011 and 2009312311024), and the State Key Laboratory of Phytochemistry and Plant Resources in West China (No. P2010-ZZ05).

Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum

Ming-Ming LI, Kou WANG, Juan HE, Li-Yan PENG, Xuan-Qin CHEN, Xiao CHENG, Qin-Shi ZHAO

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

Received:2012-03-13 Revised:2013-02-24 Online:2013-04-24 Published:2018-02-11
Supported by:
This work was financially supported by the National Basic Research Program of China (973 Program Nos. 2009CB522303 and 2011CB915503), the National Natural Science Foundation of China (Nos. 90813004 and U0932602), the projects from Chinese Academy of sciences (Nos. 2009311211011 and 2009312311024), and the State Key Laboratory of Phytochemistry and Plant Resources in West China (No. P2010-ZZ05).

摘要/Abstract

摘要： Four new labdane-type diterpenoid glycosides, laevissiosides A-D (1-4) were isolated from the 95% ethanol extract of Diplopterygium laevissimum (Christ) Nakai, along with two known analogues, 18-β-D-glucopyranosyl ester-sclareol (5) and 18-hydroxy-sclareol (6). The structures of compounds 1-4 were elucidated by extensive 1D and 2D NMR spectroscopy as well as high-resolution MS analyses. All isolated compounds were evaluated for their cytotoxic effects.

关键词: Diplopterygium laevissimum, labdane-type diterpenoid glycosides, laevissiosides

Abstract: Four new labdane-type diterpenoid glycosides, laevissiosides A-D (1-4) were isolated from the 95% ethanol extract of Diplopterygium laevissimum (Christ) Nakai, along with two known analogues, 18-β-D-glucopyranosyl ester-sclareol (5) and 18-hydroxy-sclareol (6). The structures of compounds 1-4 were elucidated by extensive 1D and 2D NMR spectroscopy as well as high-resolution MS analyses. All isolated compounds were evaluated for their cytotoxic effects.

Key words: Diplopterygium laevissimum, labdane-type diterpenoid glycosides, laevissiosides

Ming-Ming LI, Kou WANG, Juan HE, Li-Yan PENG, Xuan-Qin CHEN, Xiao CHENG, Qin-Shi ZHAO. Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum[J]. 应用天然产物, 2013, 3(2): 38-42.

Ming-Ming LI, Kou WANG, Juan HE, Li-Yan PENG, Xuan-Qin CHEN, Xiao CHENG, Qin-Shi ZHAO. Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum[J]. Natural Products and Bioprospecting, 2013, 3(2): 38-42.

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Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum

Four new labdane-type diterpenoid glycosides from Diplopterygium laevissimum

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