Dammarane-type saponins from steamed leaves of Panax notoginseng

doi:10.1007/s13659-011-0036-2

应用天然产物 ›› 2011, Vol. 1 ›› Issue (3): 124-128.DOI: 10.1007/s13659-011-0036-2

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Dammarane-type saponins from steamed leaves of Panax notoginseng

Qing LIU^a, Jun-Jiang LV^a,b, Min XU^a, Dong WANG^a, Hong-Tao ZHU^a, Chong-Ren YANG^a,c, Ying-Jun ZHANG^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100049, China;
c Weihe Biotech Research and Development Center, Yuxi 653101, China

收稿日期:2011-11-22 修回日期:2011-12-11 出版日期:2011-06-24 发布日期:2018-02-11
通讯作者: Ying-Jun ZHANG,E-mail:zhangyj@mail.kib.ac.cn
基金资助:
The authors are grateful to the members of the analytical group at State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for measuring all the spectroscopic data. This work was supported by the 973 Program of Ministry of Science and Technology of China(2011CB915503).

Dammarane-type saponins from steamed leaves of Panax notoginseng

Qing LIU^a, Jun-Jiang LV^a,b, Min XU^a, Dong WANG^a, Hong-Tao ZHU^a, Chong-Ren YANG^a,c, Ying-Jun ZHANG^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100049, China;
c Weihe Biotech Research and Development Center, Yuxi 653101, China

Received:2011-11-22 Revised:2011-12-11 Online:2011-06-24 Published:2018-02-11
Supported by:
The authors are grateful to the members of the analytical group at State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for measuring all the spectroscopic data. This work was supported by the 973 Program of Ministry of Science and Technology of China(2011CB915503).

摘要/Abstract

摘要： Four new dammarane-type triterpenoid saponins, namely notoginsenosides SFt₁-SFt₄(1-4) were isolated from the steamed leaves of Panax notoginseng(Burk.) F. H. Chen(Araliaceae), together with 17 known saponins. Their structures were established on the basis of detailed spectroscopic analyses and acidic hydrolysis. The known ginsenosides Rk₂ and Rh3 were obtained from P. notoginseng for the first time. All of these new saponins showed no in vitro cytotoxicity against five human cancer cell lines(HL-60, SMMC-7712, A-549, MCF-7, and SW480).

关键词: Panax notoginseng, steamed leave, dammarane-type saponin, notoginsenoside

Abstract: Four new dammarane-type triterpenoid saponins, namely notoginsenosides SFt₁-SFt₄(1-4) were isolated from the steamed leaves of Panax notoginseng(Burk.) F. H. Chen(Araliaceae), together with 17 known saponins. Their structures were established on the basis of detailed spectroscopic analyses and acidic hydrolysis. The known ginsenosides Rk₂ and Rh3 were obtained from P. notoginseng for the first time. All of these new saponins showed no in vitro cytotoxicity against five human cancer cell lines(HL-60, SMMC-7712, A-549, MCF-7, and SW480).

Key words: Panax notoginseng, steamed leave, dammarane-type saponin, notoginsenoside

Qing LIU, Jun-Jiang LV, Min XU, Dong WANG, Hong-Tao ZHU, Chong-Ren YANG, Ying-Jun ZHANG. Dammarane-type saponins from steamed leaves of Panax notoginseng[J]. 应用天然产物, 2011, 1(3): 124-128.

Qing LIU, Jun-Jiang LV, Min XU, Dong WANG, Hong-Tao ZHU, Chong-Ren YANG, Ying-Jun ZHANG. Dammarane-type saponins from steamed leaves of Panax notoginseng[J]. Natural Products and Bioprospecting, 2011, 1(3): 124-128.

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Dammarane-type saponins from steamed leaves of Panax notoginseng

Dammarane-type saponins from steamed leaves of Panax notoginseng

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