整合生物学期刊网

应用天然产物 ›› 2011, Vol. 1 ›› Issue (1): 37-40.DOI: 10.1007/s13659-011-0002-z

• Regular Article • 上一篇    下一篇

Cyathane diterpenoids from fruiting bodies of Phellodon niger

Sheng-Tao FANGa,b, Tao FENGa, Ling ZHANGa,b, Ze-Jun DONGa, Zheng-Hui LIa, Ji-Kai LIUa   

  1. a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China;
    b Graduate University of the Chinese Academy of Sciences, Beijing 100049, China
  • 收稿日期:2011-06-14 修回日期:2011-07-24 出版日期:2011-01-29 发布日期:2017-11-10
  • 通讯作者: Ji-Kai LIU,E-mail:jkliu@mail.kib.ac.cn
  • 基金资助:
    This project was supported by the National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Sciences Foundation of China(30830113), and MOST(2009ZX09501-029).

Cyathane diterpenoids from fruiting bodies of Phellodon niger

Sheng-Tao FANGa,b, Tao FENGa, Ling ZHANGa,b, Ze-Jun DONGa, Zheng-Hui LIa, Ji-Kai LIUa   

  1. a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China;
    b Graduate University of the Chinese Academy of Sciences, Beijing 100049, China
  • Received:2011-06-14 Revised:2011-07-24 Online:2011-01-29 Published:2017-11-10
  • Supported by:
    This project was supported by the National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Sciences Foundation of China(30830113), and MOST(2009ZX09501-029).

摘要: Four new cyathane-type diterpenoids, nigernins C-F(1-4), together with four known compounds, were isolated from the fruiting bodies of the basidiomycete Phellodon niger. The structures of these new compounds were established on the basis of spectroscopic analysis, including 1D and 2D NMR experiments. In addition, nigernin F(4) with an unusual 3, 4-seco cyathane diterpenoid skeleton was found to occur in nature for the first time. It was suggested to be as an oxidation product of C-3-C-4 bond cleavage of nigernin E(3).

关键词: cyathane, diterpenoid, nigernin, Phellodon niger

Abstract: Four new cyathane-type diterpenoids, nigernins C-F(1-4), together with four known compounds, were isolated from the fruiting bodies of the basidiomycete Phellodon niger. The structures of these new compounds were established on the basis of spectroscopic analysis, including 1D and 2D NMR experiments. In addition, nigernin F(4) with an unusual 3, 4-seco cyathane diterpenoid skeleton was found to occur in nature for the first time. It was suggested to be as an oxidation product of C-3-C-4 bond cleavage of nigernin E(3).

Key words: cyathane, diterpenoid, nigernin, Phellodon niger