整合生物学期刊网

应用天然产物 ›› 2017, Vol. 7 ›› Issue (3): 263-267.DOI: 10.1007/s13659-017-0128-8

• Original article • 上一篇    下一篇

New Diterpenoids from Clerodendranthus spicatus

Ya-Mei Li1,2, Bing Xiang1, Xiao-Zheng Li1,2, Yong-Ming Yan2, Yong-Xian Cheng1,2   

  1. 1. Yunnan University of Traditional Chinese Medicine, Kunming 650504, People's Republic of China;
    2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China
  • 收稿日期:2017-03-01 修回日期:2017-04-18 出版日期:2017-06-24 发布日期:2018-02-06
  • 通讯作者: Yong-Ming Yan,e-mail:yanym@mail.kib.ac.cn;Yong-Xian Cheng,e-mail:yxcheng@mail.kib.ac.cn
  • 基金资助:
    This study was financially supported by grants from Center of Cooperative Innovation for South China Medicine of Yunnan Province and National Science Fund for Distinguished Young Scholars (81525026).

New Diterpenoids from Clerodendranthus spicatus

Ya-Mei Li1,2, Bing Xiang1, Xiao-Zheng Li1,2, Yong-Ming Yan2, Yong-Xian Cheng1,2   

  1. 1. Yunnan University of Traditional Chinese Medicine, Kunming 650504, People's Republic of China;
    2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China
  • Received:2017-03-01 Revised:2017-04-18 Online:2017-06-24 Published:2018-02-06
  • Supported by:
    This study was financially supported by grants from Center of Cooperative Innovation for South China Medicine of Yunnan Province and National Science Fund for Distinguished Young Scholars (81525026).

摘要: Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 lM.

关键词: Clerodendranthus spicatus, Diterpenoid, Neoorthosiphonones B and C

Abstract: Two new diterpenoids, neoorthosiphonones B and C (1 and 2), and one known diterpenoid, were isolated from the aerial parts of Clerodendranthus spicatus. Their structures including absolute configurations were determined by comprehensive spectroscopic analyses and X-ray crystallographic methods. No compound was found to inhibit fibronectin production at the concentration of 20 lM.

Key words: Clerodendranthus spicatus, Diterpenoid, Neoorthosiphonones B and C