Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

doi:10.1007/s13659-014-0047-x

应用天然产物 ›› 2015, Vol. 5 ›› Issue (1): 23-28.DOI: 10.1007/s13659-014-0047-x

• Original article • 上一篇下一篇

Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

Zhen-Zhu Zhao^1,2, He-Ping Chen^1,2, Tao Feng¹, Zheng-Hui Li¹, Ze-Jun Dong¹, Ji-Kai Liu¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China

收稿日期:2014-10-24 修回日期:2014-11-18 出版日期:2015-02-24 发布日期:2018-02-11
通讯作者: Ji-Kai Liu,e-mail:jkliu@mail.kib.ac.cn
基金资助:
This work was financially supported by National Natural Science Foundation of China(U1132607, 81102346), and Natural Science Fund of Yunnan province(2011FB099).

Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

Zhen-Zhu Zhao^1,2, He-Ping Chen^1,2, Tao Feng¹, Zheng-Hui Li¹, Ze-Jun Dong¹, Ji-Kai Liu¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China

Received:2014-10-24 Revised:2014-11-18 Online:2015-02-24 Published:2018-02-11
Supported by:
This work was financially supported by National Natural Science Foundation of China(U1132607, 81102346), and Natural Science Fund of Yunnan province(2011FB099).

摘要/Abstract

摘要： Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol(1), 11-hydroxyacetoxydrim-7-en-3β-ol(2), 2, 6-dimethyl-7, 10-epoxy-10-hydroxymethyldodeca-2, 11-dien-6-ol(3), and 7, 10-epoxy-2, 6, 10-trimethyldodeca-2, 11-diene-4, 6-diol(4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1-4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities.

关键词: Phellinidium sulphurascens, Drimane, 7,10-Epoxy-2,6,10-trimethyldodeca-2,11-diene

Abstract: Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol(1), 11-hydroxyacetoxydrim-7-en-3β-ol(2), 2, 6-dimethyl-7, 10-epoxy-10-hydroxymethyldodeca-2, 11-dien-6-ol(3), and 7, 10-epoxy-2, 6, 10-trimethyldodeca-2, 11-diene-4, 6-diol(4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1-4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities.

Key words: Phellinidium sulphurascens, Drimane, 7,10-Epoxy-2,6,10-trimethyldodeca-2,11-diene

Zhen-Zhu Zhao, He-Ping Chen, Tao Feng, Zheng-Hui Li, Ze-Jun Dong, Ji-Kai Liu. Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens[J]. 应用天然产物, 2015, 5(1): 23-28.

Zhen-Zhu Zhao, He-Ping Chen, Tao Feng, Zheng-Hui Li, Ze-Jun Dong, Ji-Kai Liu. Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens[J]. Natural Products and Bioprospecting, 2015, 5(1): 23-28.

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[3]	Jiang-Bo He, Tao Feng, Shen Zhang, Ze-Jun Dong, Zheng-Hui Li, Hua-Jie Zhu, Ji-Kai Liu. Seven New Drimane-Type Sesquiterpenoids from Cultures of Fungus Phellinus tuberculosus[J]. 应用天然产物, 2014, 4(1): 21-25.
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Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

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