应用天然产物 ›› 2015, Vol. 5 ›› Issue (1): 17-22.DOI: 10.1007/s13659-014-0045-z
Rong-Hua Yin1,2, Zhen-Zhu Zhao1,2, Xu Ji1, Ze-Jun Dong1, Zheng-Hui Li1, Tao Feng1, Ji-Kai Liu1
收稿日期:
2014-09-16
修回日期:
2014-10-30
出版日期:
2015-02-24
发布日期:
2018-02-11
通讯作者:
Ji-Kai Liu,e-mail:jkliu@mail.kib.ac.cn
基金资助:
Rong-Hua Yin1,2, Zhen-Zhu Zhao1,2, Xu Ji1, Ze-Jun Dong1, Zheng-Hui Li1, Tao Feng1, Ji-Kai Liu1
Received:
2014-09-16
Revised:
2014-10-30
Online:
2015-02-24
Published:
2018-02-11
Supported by:
摘要: Two new steroids, 3α, 17α, 19, 20-tetrahydroxy-4α-methylpregn-8-ene(1) and 3α, 12α, 17α, 20-tetrahydroxy-4α-methylpregn-8-ene(2) and three new sesquiterpenoids, 12-hydroxy-α-cadinol(3), 3α, 12-dihydroxy-δ-cadinol(4), and 3α, 6α-dihydroxyspiroax-4-ene(5), have been isolated from cultures of the fungus Phellinus igniarius. Their structures were characterized based on extensive spectroscopic data. In preliminary in vitro assays, compounds 3 and 4 exhibited the vascular-activities against phenylephrine-induced vasoconstriction with the relaxing rates of 11.0% and 7.0% at 3×10-4 M, respectively.
Rong-Hua Yin, Zhen-Zhu Zhao, Xu Ji, Ze-Jun Dong, Zheng-Hui Li, Tao Feng, Ji-Kai Liu. Steroids and Sesquiterpenes From Cultures of the Fungus Phellinus igniarius[J]. 应用天然产物, 2015, 5(1): 17-22.
Rong-Hua Yin, Zhen-Zhu Zhao, Xu Ji, Ze-Jun Dong, Zheng-Hui Li, Tao Feng, Ji-Kai Liu. Steroids and Sesquiterpenes From Cultures of the Fungus Phellinus igniarius[J]. Natural Products and Bioprospecting, 2015, 5(1): 17-22.
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