应用天然产物 ›› 2014, Vol. 4 ›› Issue (1): 1-19.DOI: 10.1007/s13659-014-0005-7
• Review • 下一篇
Lydia L. Lifongo1, Conrad V. Simoben1, Fidele Ntie-Kang1, Smith B. Babiaka1, Philip N. Judson2,3
收稿日期:
2013-12-26
修回日期:
2014-02-10
出版日期:
2014-02-24
发布日期:
2018-02-11
通讯作者:
Fidele Ntie-Kang,e-mail:ntiekfidele@gmail.com
Lydia L. Lifongo1, Conrad V. Simoben1, Fidele Ntie-Kang1, Smith B. Babiaka1, Philip N. Judson2,3
Received:
2013-12-26
Revised:
2014-02-10
Online:
2014-02-24
Published:
2018-02-11
摘要: Traditional medicinal practices play a key role in health care systems in countries with developing economies. The aim of this survey was to validate the use of traditional medicine within local Nigerian communities. In this review, we examine the ethnobotanical uses of selected plant species from the Nigerian flora and attempt to correlate the activities of the isolated bioactive principles with known uses of the plant species in African traditional medicine. Thirty-three(33) plant species were identified and about 100 out of the 120 compounds identified with these plants matched with the ethnobotanical uses of the plants.
Lydia L. Lifongo, Conrad V. Simoben, Fidele Ntie-Kang, Smith B. Babiaka, Philip N. Judson. A Bioactivity Versus Ethnobotanical Survey of Medicinal Plants from Nigeria,West Africa[J]. 应用天然产物, 2014, 4(1): 1-19.
Lydia L. Lifongo, Conrad V. Simoben, Fidele Ntie-Kang, Smith B. Babiaka, Philip N. Judson. A Bioactivity Versus Ethnobotanical Survey of Medicinal Plants from Nigeria,West Africa[J]. Natural Products and Bioprospecting, 2014, 4(1): 1-19.
1. E.C. Raphael, Res. J. Pharmacol. 5(6), 90-94 (2011) 2. O. Jansen, M. Tits, L. Angenot, J. Nicolas, P. De Mol, J. Nikiema, M. Frédérich, Malar. J. 11, 1-9 (2012) 3. W.R. Sawadogo, A. Maciuk, J.T. Banzouzi, P. Champy, B. Figadere, I.P. Guissou, O.G. Nacoulma, Nat. Prod. Res. 26(6), 575-579 (2012) 4. S.Y. Kamble, S.R. Patil, P.S. Sawant, S. Sawant, S.G. Pawar, E.A. Singh, J. Indian, Tradit. Knowl. 9(3), 591-598 (2010) 5. I.A. Ekpo, R.B. Agbor, A.N. Osuagwu, B.E. Ekanem, E.C. Okpako, I.S. Urua, World J. Biol. Res. 5(2), 41-44 (2012) 6. Thomas, G. Medicinal Chemistry (Wiley, Southern Gate, Chichester, 2007), p 15. www.wileyeurope.com 7. World Health Organization (WHO) Facts sheet http://www.who.int/mediacentre/news/releases/2004/pr44/en/. Accessed on 03 Dec 2013 8. K. Busia, Phytother. Res. 19, 919-923 (2005) 9. World Health Organisation:Traditional medicine. Fact sheet No 134 (WHO, Geneva, 2003) 10. F.B. Magassouba, A. Diallo, M. Kouyate, F. Mara, O. Mara, O. Bangoura, A. Camara, S. Traore, A.K. Diallo, M. Zaoro, K. Lamah, S. Diallo, G. Camara, S. Traore, A. Keita, M.K. Camara, R. Barry, S. Keita, K. Oulare, M.S. Barry, M. Donzo, K. Camara, K. Tote, D. Vanden Berghe, J. Totte, L. Pieters, A.J. Vlietinck, A.M. Balde, J. Ethnopharmacol. 114, 44-53 (2007) 11. F.M.D. Ogbe, O.L. Eruogun, M. Uwagboe, Sci. Res. Essay. 4(3), 120-130 (2009) 12. N.R.A. Ngono, M.M.L. Koanga, T.A. Tchinda, N.H. Magnifouet, C.P.R. Motso, B.Z. Mballa, E.R.M. Ebelle, F. Ndifor, L. Biyiti, Z.P.H. Amvam, Afr. J. Plant. Sci. 5(1), 15-21 (2001) 13. F. Ntie-Kang, J.A. Mbah, L.M. Mbaze, L.L. Lifongo, M. Scharfe, J. Ngo Hanna, F. Cho-Ngwa, P.A. Onguéné, L.C.O. Owono, E. Megnassan, W. Sippl, S.M.N. Efange, BMC Complement. Altern. Med. 13, 88 (2013) 14. P.S. Njomnang, F. Benoit-Vical, J. Ethnopharmacol. 114, 130-140 (2007) 15. A. Ramazani, S. Zakeri, S. Sardari, N. Khodakarim, N. Djadidt, Malar. J. 9, 124-131 (2010) 16. O. Kayser, A.F. Kiderlen, H. Laatsch, S.L. Croft, Acta Trop. 77, 307-314 (2000) 17. M.A. Sonibare, Z.O. Gbile, Afr. J. Trad. CAM. 5(4), 340-345 (2008) 18. A. Adamu, E.M. Abdurahman, H. Ibrahim, M.S. Abubakar, M.G. Magaji, A.H. Yaro, Niger. J. Pharm. Sci. 6(2), 1-6 (2007) 19. O. Silva, A. Duarte, M. Pimentel, S. Viegas, H. Barroso, J. Machado, J. Ethnopharmacol. 57, 203-207 (1997) 20. M.S. Abubakar, A.M. Musa, A. Ahmed, I.M. Hussaini, J. Ethnopharmacol. 111, 625-629 (2007) 21. Y.J. Xu, R.I. Capistrano, L. Dhooghe, K. Foubert, F. Lemière, S. Maregesi, A. Baldé, S. Apers, L. Pieters, Planta Med. 77, 1139-1148 (2011) 22. M. Idu, J.O. Erhabor, H.M. Efijuemue, Trop. J. Pharm. Res. 9(2), 110-118 (2010) 23. R. Sanogo, Afr. J. Tradit. CAM. 8, 90-96 (2011) 24. Administrative Map of Nigeria-Nations Online Project. www. nationsonline.org 25. O.C. Library, in Country Profile:Nigeria 2008, pp. 1-23 26. B.A. Usman, L.L. Adefalu, Trop. Conserv. Biodivers. 11(3-4), 44-52 (2010) 27. E.O. Ogbadoyi, A.O. Abdulganiy, T.Z. Adama, J.I. Okogun, J. Ethnopharmacol. 112, 85-89 (2007) 28. D.A. Akinpelu, T.M. Onakoya, Afr. J. Biotechnol. 5(11), 1078-1081 (2006) 29. I.P. Dike, O.O. Obembe, F.E. Adebiyi, J. Ethnopharmacol. 144(3), 618-626 (2012) 30. S.E. Atawodi, D.A. Ameh, S. Ibrahim, J.N. Andrew, H.C. Nzelibe, E.O. Onyike, K.M. Anigo, E.A. Abu, D.B. James, G.C. Njoku, A.B. Sallau, J. Ethnopharmacol. 79, 279-282 (2002) 31. K.A. Abo, A.A. Fred-jaiyesimi, A.E.A. Jaiyesimi, J. Ethnopharmacol. 115, 67-71 (2008) 32. M.O. Soladoye, M.O. Adetayo, E.C. Chukwuma, A.N. Adetunji, Ann. Biol. Res. 1(4), 1-15 (2010) 33. O.A. Idowu, O.T. Soniran, O. Ajana, D.O. Aworinde, Afr. J. Pharm. Pharmacolol. 4(2), 55-60 (2010) 34. K.K. Ajibesin, B.A. Ekpo, D.N. Bala, E.E. Essien, S.A. Adesanya, J. Ethnopharmacol. 115, 387-408 (2008) 35. A. Adetutu, W.A. Morgan, O. Corcoran, J. Ethnopharmacol. 137(1), 50-56 (2011) 36. A.A. Gbolade, J. Ethnopharmacol. 121, 135-139 (2009) 37. A.A. Gbolade, J. Ethnopharmacol. 144(1), 1-10 (2012) 38. M. Idu, A.A. Umweni, T. Odaro, L. Ojelede, Ethnobot. Leafl. 13, 548-563 (2009) 39. F. Ntie-Kang, L.L. Lifongo, L.M. Mbaze, N. Ekwelle, L.C. Owono Owono, E. Megnassan, P.N. Judson, W. Sippl, S.M.N. Efange, BMC Complement. Altern. Med. 13, 147 (2013) 40. D. Zofou, F. Ntie-Kang, W. Sippl, S.M.N. Efange, Nat. Prod. Rep. 30, 1098-1120 (2013) 41. F. Ntie-Kang, P. Amoa Onguéné, M. Scharfe, L.M. Mbaze, L.C. Owono Owono, E. Megnassan, W. Sippl, S.M.N. Efange, RSC Adv. 4, 409-419 (2014) 42. F. Ntie-Kang, L.L. Lifongo, J.A. Mbah, L.C. Owono Owono, E. Megnassan, L.M. Mbaze, P.N. Judson, W. Sippl, S.M.N. Efange, In Silico Pharmacol 1, 12 (2013) 43. F. Ntie-Kang, J.A. Mbah, L.L. Lifongo, L.C. Owono Owono, E. Megnassan, L.M. Mbaze, P.N. Judson, W. Sippl, S.M.N. Efange, Org. Med. Chem. Lett. 3, 10 (2013) 44. F. Ntie-Kang, D. Zofou, S.B. Babiaka, R. Meudom, M. Scharfe, L.L. Lifongo, J.A. Mbah, L.M. Mbaze, W. Sippl, S.M.N. Efange, PLoS ONE 8(10), e78085 (2013) 45. J.O. Adebayo, A.U. Krettli, J. Ethnopharmacol. 133, 289-302 (2011) 46. H.A. Perez, M. De La Rosa, R. Apitz, Antimicrob. Agents Chemother. 38, 337-339 (1994) 47. A. Coppi, M. Cabinian, D. Mirelman, P. Sinnis, Antimicrob. Agents Chemother. 50, 1731-1737 (2006) 48. S.O. Okpo, O.O. Adeyemi, A.A. Onakade, West Afr. J. Pharmacol. Drug Res. 4 (2008). http://dx.doi.org/10.4314/wajpdr.v24i1.59046 49. C.C.A. Azikiwe, I.M. Siminialayi, N. Brambaifa, L.U. Amazu, J.C. Enye, M.C. Ezeani, Asian Pac. J. Trop. Dis. 4(Suppl 1), S446-S452 (2012) 50. P.J. Houghton, J.M. Agbedahunsi, A. Adegbulugbe, Phytochemistry 65, 2893-2896 (2004) 51. Y.H. Kim, E.J. Park, M.H. Park, U. Badarch, G.M. Woldemichael, J.A. Beutler, Biol. Pharm. Bull. 29(10), 2140-2142 (2006) 52. K. Bhadra, G.S. Kumar, Med. Res. Rev. 31(6), 821-862 (2011) 53. G. Bidla, V.P. Titanji, B. Joko, G.E. Ghazali, A. Bolad, K. Berzins, Ind. J. Pharmacol. 36, 245-246 (2004) 54. F. Jia, G. Zou, J. Fan, Z. Yuan, Arch. Virol. 155(8), 1325-1329 (2010) 55. K. Ezeamuzie, M.C. Ojinnaka, E.O. Uzogara, S.E. Orji, Afr. J. Med. Med. Sci. 23, 85-90 (1994) 56. J.E. Okokon, B.S. Antia, A.C. Igboasoiyi, E.E. Essien, H.O. Mbagwu, J. Ethnopharmacol. 111, 464-467 (2007) 57. E. Elisabetsky, L. Costa-Campos, eCAM 3(1), 39-48 (2006) 58. L.S. Kasim, V.A. Ferro, O.A. Odukoya, A. Drummond, G.E. Ukpo, V. Seidel, A.I. Gray, R.J. Waigh, Microbiol. Antimicrob. 3(1), 13-17 (2011) 59. S.M. Kupchan, R.J. Hemingway, A. Karim, D. Werner, J. Org. Chem. 34(12), 3908-3911 (1969) 60. J. Liobikas, D. Majiene, S. Trumbeckaite, L. Kursvietiene, R. Masteikova, D.M. Kopustinskiene, A. Savickas, J. Bernatoniene, J. Nat. Prod. 74(7), 1640-1644 (2011) 61. S.C. Gnoatto, A. Dassonville-Klimpt, S. Da Nascimento, P. Galéra, K. Boumediene, G. Gosmann, P. Sonnet, S. Moslemi, Eur. J. Med. Chem. 43(9), 1865-1877 (2008) 62. C.A. Elusiyan, N.C. Ani, C.O. Adewunmi, T.A. Olugbade, Afr. J. Tradit. CAM. 8(1), 27-33 (2011) 63. P. Picerno, G. Autore, S. Marzocco, M. Meloni, R. Sanogo, R.P. Aquino, J. Nat. Prod. 68(11), 1610-1614 (2005) 64. E.O. Iwalewa, L. Lege-Oguntoye, P.P. Rai, T.T. Iyaniwura, N.L. Etkin, West Afr. J. Pharmaceut. Drug Res. 9, 19-21 (1990) 65. C. Ancolio, N. Azas, V. Mahiou, E. Ollivier, C. Di Giorgio, A. Keita, P. Timon-David, G. Balansard, Phytother. Res. 16, 646-649 (2002) 66. H. Combier, M. Becchi, A. Cavé, Plantes Médicinales et Phytothérapie 11, 251-253 (1977) 67. O. Silva, E.T. Gomes, J. Nat. Prod. 66(3), 447-449 (2003) 68. M. Kuroda, A. Yokosuka, R. Kobayashi, M. Jitsuno, H. Kando, K. Nosaka, H. Ishii, T. Yamori, Y. Mimaki, Chem. Pharm. Bull. 55, 1240-1244 (2007) 69. I. Castillo-Juarez, V. Gonzalez, H. Jaime-Aguilar, G. Martínez, E. Linares, R. Bye, I. Romero, J. Ethnopharmacol. 122, 402-405 (2009) 70. J.O. Adebayo, E.A. Balogun, S.A. Oyeleke, Phcog. Res. 1, 143-147 (2009) 71. E. Goffin, E. Ziemons, P. De Mol, M. de Ceu de Madureira, A.P. Martins, A. Proenca da Cunha, G. Philippe, M. Tits, L. Angenot, M. Frederich, Planta Med. 68, 543-545 (2002) 72. M.E. Sanchez-Mendoza, A. Reyes-Ramírez, L.C. Antonio, L.M. Jiménez, J. Rodríguez-Silverio, J. Arrieta, Molecules 16, 665-674 (2011) 73. H.O. Egharevba, M.S. Abdullahi, S.K. Okwute, J.I. Okogun, Researcher 2(10), 35-40 (2010) 74. Y. Zhao, J. Yue, Z. Lin, J. Ding, H. Sun, Phytochemistry 44, 459-464 (1997) 75. A.A. Ahmadu, H.S. Hassan, M.U. Abubakar, I.N. Akpulu, Afr. J. Trad. CAM. 4(3), 257-260 (2007) 76. F.O. Ogungbamila, G.O. Onawunmi, O. Adeosun, Nat. Prod. Lett. 10, 201-203 (1997) 77. S. Jang, K.W. Kelley, R.W. Johnson, Proc. Natl. Acad. Sci. U.S.A. 105(21), 7534-7539 (2008) 78. T.C. Theoharides, J. Neuroinflammation 6, 29 (2009) 79. G. Zhao, G.W. Qin, J. Wang, W.J. Chu, L.H. Guo, Neurochem. Int. 56(1), 168-176 (2010) 80. M.C. Yu, J.H. Chen, C.Y. Lai, C.Y. Han, W.C. Ko, Eur. J. Pharmacol. 10627(1-3), 269-275 (2010) 81. S. Byun, K.W. Lee, S.K. Jung, E.J. Lee, M.K. Hwang, S.H. Lim, A.M. Bode, H.J. Lee, Z. Dong, Cancer Res. 70, 2415-2423 (2010) 82. M. López-Lazaro, Mini Rev. Med. Chem. 9(1), 31-59 (2009) 83. B.A. Adeniyi, M.F. Robert, H. Chai, H.H.S. Fong, Phytother. Res. 17, 282-284 (2003) 84. T.A. Tor-Anyiin, R. Shaato, H.O.A. Oluma, J. Herbs Spices Med. Plants 10, 61-74 (2003) 85. J.T. Banzouzi, R. Prado, H. Menan, A. Valentin, C. Roumestan, M. Mallie, Y. Pelissier, Y. Blache, J. Ethnopharmacol. 81, 399-401 (2002) 86. F.B.C. Okoye, P.O. Osadebe, C.S. Nworu, N.N. Okoye, E.O. Omeje, C.O. Esimone, Nat. Prod. Lett. 25(20), 1941-1949 (2011) 87. F.B.C. Okoye, P.O. Osadebe, Nat. Prod. Lett. 24(3), 266-273 (2010) 88. A. Falodun, T.C. Onwudiwe, Nnena, Bayero J. Pure Appl. Sci. 4(2), 1-4 (2011) 89. J.S. Ashidi, P.J. Houghton, P.J. Hylands, T. Efferth, J. Ethnopharmacol. 128, 501-512 (2010) 90. B.Z. Ahn, U. Degen, C. Lienjayetz, P. Pachaly, F. Zymalkowski, Arch. Pharm. 311, 569-578 (1978) 91. T. Matsumoto, T. Kobayashi, K. Ishida, Y. Hirasawa, H. Morita, T. Honda, K. Kamata, Biol. Pharm. Bull. 33(5), 844-848 (2010) 92. L.N. Ofodile, N. Uma, R.J. Grayer, O.T. Ogundipe, M.S.J. Simmonds, Phytother. Res. 26, 748-751 (2012) 93. R.R. Paterson, Phytochemistry 67(18), 1985-2001 (2006) 94. R.S. El Dine, A.M. El Halawany, C.M. Ma, M. Hattori, J. Nat. Prod. 71, 1022-1026 (2008) 95. J.C. Chukwujekwu, P. Smith, P.H. Coombes, D.A. Mulholland, J. van Staden, J. Ethnopharmacol. 102, 295-297 (2005) 96. D.E. Okwu, F.U. Nnamdi, Der. Chem. Sin. 2(2), 247-254 (2011) 97. N.M. Enwerem, J.I. Okogun, C.O. Wambebe, D.A. Okorie, P.A. Akah, Phytomedicine 8(2), 112-114 (2001) 98. S. Muhammad, N.A. Amusa, Res. J. Agric. Biol. Sci. 1, 254-260 (2005) 99. C. Limmatvapirat, S. Sirisopanaporn, P. Kittakoop, Planta Med. 70, 276-278 (2004) 100. E.O. Ajaiyeoba, J.S. Ashidi, L.C. Okpako, P.J. Houghton, C.W. Wright, Phytother. Res. 22, 254-255 (2008) 101. H. Morita, S. Oshimi, Y. Hirasawa, K. Koyama, T. Honda, W. Ekasari, G. Indrayanto, N.C. Zaini, Org. Lett. 9, 3691-3693 (2007) 102. S. Oshimi, Y. Tomizawa, Y. Hirasawa, T. Honda, W. Ekasari, A. Widyawaruyanti, M. Rudyanto, G. Indrayanto, N.C. Zaini, H. Morita, Bioorg. Med. Chem. Lett. 18, 3761-3763 (2008) 103. M.O. Agbo, D. Lai, F.B.C. Okoye, P.O. Osadebe, P. Proksch, Fitoterapia 86, 78-83 (2013) 104. E.O. Omeje, P.O. Osadebe, C.S. Nworu, J.N. Nwodo, W.O. Obonga, A. Kawamura, C.O. Esimone, P. Proksch, Pharmaceut. Biol. 49(12), 1271-1276 (2011) 105. G.C. Obute, Ethnomedicinal Plant Resources of South eastern Nigeria. Ethnobotanical Leaflets, 2005. http://www.siu.edu/*ebl/leaflets/obute.htm 106. S. Bertani, G. Bourdy, I. Landau, J.C. Robinson, P. Esterre, E. Deharo, J. Ethnopharmacol. 98, 45-54 (2005) 107. J.T. Banzouzi, R. Prado, H. Menan, A. Valentin, C. Roumestan, M. Mallie, Y. Pelissier, Y. Blache, Phytomedicine 11, 338-341 (2004) 108. D. Karou, M.H. Dicko, S. Sanon, J. Simpore, A.S. Traore, J. Ethnopharmacol. 89, 291-294 (2003) 109. V.Y.A. Barku, Y. Opoku-Boahen, E.Y. Dzotsi, Int. Res. J. Biochem. Bioinform. 2, 58-61 (2012) 110. K. Cimanga, T. De Bruyne, L. Peters, M. Claeys, A. Vlietinck, Tetrahedron Lett. 37, 1703-1706 (1996) 111. K. Cimanga, T. De Bruyne, L. Peters, A.J. Vlietinck, J. Nat. Prod. 60, 688-691 (1997) 112. S.Y. Ablordeppey, C.D. Hufford, R.F. Bourne, D. DwumaBadu, Planta Med. 56, 416 (1990) 113. A. Paulo, E.T. Gomes, J. Steele, D.C. Warhurst, P.J. Houghton, Planta Med. 66, 30-34 (2000) 114. C.E. Hadden, M.H.M. Sharaf, J.E. Guido, R.H. Robins, A.N. Tackie, C.H. Phoebe Jr, P.L. Schiff Jr, G.E. Martin, J. Nat. Prod. 62, 238-240 (1999) 115. A.B. Isah, Y.K. Ibrahim, E.O. Iwalewa, Phytother. Res. 17, 807-810 (2003) 116. J.M. Agbedahunsi, A.A. Elujoba, J.M. Makinde, A.M.J. Oduda, Pharm. Biol. 36, 8-12 (1998) 117. J.M. Agbedahunsi, A.A. Elujoba, Nig. J. Nat. Prod. Med. 2, 34-36 (1998) 118. J. Bickii, N. Nijifutie, J.A. Foyere, L.K. Basco, P. Ringwald, J. Ethnopharmacol. 69, 27-33 (2000) 119. S.G. Kamath, N. Chen, Y. Xiong, R. Wenham, S. Apte, M. Humphrey, J. Cragun, J.M. Lancaster, Int. J. Gynecol. Cancer 19(9), 1564-1569 (2009) 120. G.E.L. Brandt, M.D. Schmidt, T.E. Prisinzano, B.S.J. Blagg, J. Med. Chem. 51(20), 6495-6502 (2008) 121. I.A. Bello, G.I. Ndukwe, O.T. Audu, J.D. Habila, Org. Med. Chem. Lett. 1, 14 (2011) 122. T.O. Idowu, A.O. Ogundaini, A.O. Salau, E.M. Obuotor, M. Bezabih, B.M. Abegaz, Phytochemistry 71, 2092-2098 (2010) 123. S.O. Awe, J.M. Makinde, Ind. J. Pharmacol. 30, 51-53 (1998) 124. R.K. Cimanga, G.L. Tona, G.K. Mesia, O.K. Kambu, D.P. Bakana, P.D.T. Kalenda, A.O. Penge, J.J.T. Muyembe, J. Totté, L. Pieters, A.J. Vlietinck, Pharm. Biol. 44, 677-681 (2006) 125. O.O. Odebiyi, E.S. Sofowora, Planta Med. 36, 204-207 (1979) 126. E.O. Ajaiyeoba, U.I. Abalogu, H.C. Krebs, A.M.J. Oduola, J. Ethnopharmacol. 67, 321-325 (1999) 127. S. Bertani, E. Houël, D. Stien, L. Chevolot, V. Jullian, G. Garavito, G. Bourdy, E. Deharo, J. Ethnopharmacol. 108, 155-157 (2006) 128. I. Kitagawa, T. Mahmud, K.I. Yokota, S. Nakagawa, T. Mayumi, M. Kobayashi, H. Shibuya, Chem. Pharm. Bull. 41, 2009-2014 (1996) 129. N. Cachet, F. Hoakwie, S. Bertani, G. Bourdy, E. Deharo, D. Stien, E. Houel, H. Gornitzka, J. Fillaux, S. Chevalley, A. Valentin, V. Jullian, Antimicrob. Agents Chemother. 53(10), 4393-4398 (2009) 130. O.A. Odukoya, P.J. Houghton, A. Raman, Phytomedicine 6(4), 251-256 (1999) 131. V.P.K. Titanji, D. Zofou, M.N. Ngemenya, Afr. J. Trad. CAM. 5, 302-321 (2008) 132. V. Kuete, T. Efferth, Front. Pharmacol. 1, 123 (2010) 133. J.J. Magadula, P. Erasto, Nat. Prod. Rep. 26, 1535-1554 (2009) 134. P. Amoa Onguéné, F. Ntie-Kang, L.L. Lifongo, J.C. Ndom, W. Sippl, L.M. Mbaze, Malar. J. 12, 449 (2013) |
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