整合生物学期刊网

应用天然产物 ›› 2013, Vol. 3 ›› Issue (6): 271-276.DOI: 10.1007/s13659-013-0065-0

• Regular Article • 上一篇    下一篇

Sesquiterpenoids and an ergosterol from cultures of the fungus Daedaleopsis tricolor

Jiang-Yuan ZHAOa,b, Tao FENGb, Zheng-Hui LIa, Ze-Jun DONGa, Hong-Bin ZHANGb, Ji-Kai LIUa   

  1. a State Key Laboratory of Phytochemistry, Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
    b Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, School of Chemical Science, Technology, Yunnan University, Kunming 650091, China
  • 收稿日期:2013-08-21 修回日期:2013-11-10 出版日期:2013-12-24 发布日期:2018-02-11
  • 通讯作者: Ji-Kai LIU,E-mail:jkliu@mail.kib.ac.cn
  • 基金资助:
    This work was financially supported by the National Natural Science Foundation of China (U1132607).

Sesquiterpenoids and an ergosterol from cultures of the fungus Daedaleopsis tricolor

Jiang-Yuan ZHAOa,b, Tao FENGb, Zheng-Hui LIa, Ze-Jun DONGa, Hong-Bin ZHANGb, Ji-Kai LIUa   

  1. a State Key Laboratory of Phytochemistry, Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
    b Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, School of Chemical Science, Technology, Yunnan University, Kunming 650091, China
  • Received:2013-08-21 Revised:2013-11-10 Online:2013-12-24 Published:2018-02-11
  • Supported by:
    This work was financially supported by the National Natural Science Foundation of China (U1132607).

摘要: Four new bisabolane sesquiterpenoids daedatrins A-D (1-4), a cadinane sesquiterpene 12-hydroxy-α-cadinol (5), a heptanorergosterane derivative daedatrin G (6) were isolated from cultures of the basidiomycete Daedaleopsis tricolor. Their structures were elucidated by spectroscopic methods including extensive 2D NMR techniques, X-ray crystallography. All the compounds showed no significant activity against five human cancer cell lines.

关键词: Daedaleopsis tricolor, sesquiterpenoid, ergosterane

Abstract: Four new bisabolane sesquiterpenoids daedatrins A-D (1-4), a cadinane sesquiterpene 12-hydroxy-α-cadinol (5), a heptanorergosterane derivative daedatrin G (6) were isolated from cultures of the basidiomycete Daedaleopsis tricolor. Their structures were elucidated by spectroscopic methods including extensive 2D NMR techniques, X-ray crystallography. All the compounds showed no significant activity against five human cancer cell lines.

Key words: Daedaleopsis tricolor, sesquiterpenoid, ergosterane