Anti-inflammatory and Antioxidant Activity of Cinnamomum longepaniculatum Essential Oil

doi:10.7525/j.issn.1673-5102.2016.06.020

Abstract

Abstract: Anti-inflammatory effect of Cinnamomum longepaniculatum essential oil on LPS-induced RAW264.7 macrophages inflammation was observed by MTT test and the content of NO. In vivo, anti-inflammatory activity was carried by checking carrageenan-induced rat paw swelling degree treated with C.longepaniculatum essential oil. The antioxidant capacity was determined by measuring DPPH·radical scavenging ability. C.longepaniculatum essential oil can reduce the inhibition rate and NO production of the LPS-induced RAW264.7 macrophage and it can also reduce carrageenan-induced rat paw swelling with dose-dependent manner. C.longepaniculatum essential oil can induce DPPH radical scavenging rate increased significantly, and the effect is more significant with time. Therefore, C.longepaniculatum oil has anti-inflammatory and anti-oxidant activity.

Key words: Cinnamomum longepaniculatum, essential oil, anti-inflammatory activity, antioxidant activity

CLC Number:

S792.23

CONG Ying, ZHANG Lin, ZU Yuan-Gang, YANG Lei, ZAN Peng. Anti-inflammatory and Antioxidant Activity of Cinnamomum longepaniculatum Essential Oil[J]. Bulletin of Botanical Research, 2016, 36(6): 949-954.

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