Abstract:

Delay of germination 1 (DOG1) is a master regulator of seed dormancy and cooperates with abscisic acid (ABA) to delay seed germination. The core ABA signaling pathway and DOG1 pathway converge in protein phosphatase 2C (PP2C). DOG1 requires PP2C to regulate seed dormancy and enhances ABA signaling by binding to ABA HYPERSENSITIVE GERMINATION 1/3 (AHG1/AHG3). DOG1 suppresses AHG1 activity to increase ABA sensitivity and induce seed dormancy. In recent years, significant progress has been made in research on the regulation of seed dormancy and germination by DOG1. In this review, we summarize research achievements in this field, including the role of DOG1 in seed maturation, dormancy, and germination, the transcriptional regulatory mechanisms of DOG1 expression, and the regulation and action mechanism of DOG1 on seed dormancy and germination. We also highlight scientific issues that need to be further investigated in this field.

摘要：

DOG1（Delay of germination 1）蛋白是种子休眠的一种主要调控因子，可与ABA协同作用来延迟种子萌发。核心脱落酸（ABA）信号转导途径和DOG1途径在蛋白磷酸酶2C（PP2C）中汇聚。DOG1调控种子休眠需要PP2C，并通过与ABA过敏感萌发（AHG1/AHG3）结合来增强ABA的信号转导。DOG1抑制AHG1的作用来增加ABA的敏感性和诱导种子休眠。近年来，DOG1对种子休眠与萌发的调控研究取得了显著进展。本文对该领域的研究成果进行了综述，主要包括：DOG1对种子成熟、休眠与萌发的作用，DOG1表达的转录调控机制以及DOG1对种子休眠与萌发的调控及作用机制，最后提出了在本领域需要进一步研究的科学问题。