Abstract: Investigation of the chemical constituents of the leaves of Craibiodendron yunnanense obtained the isolation of fifteen compounds . Their structures were elucidated as asebotoxin-III ( 1) , grayanotoxin-XVIII (2) , leucothol A ( 3) , proA-4 (4) , quercetin-3-O-β-galactoside ( 5) , quercetin-3-O-α- arabinofuranoside (6) , quercetin-3-O-α-rhamnopyranoside (7) , trihydroxyflavone-3-O-α-rhamnopyranoside (8 ) , 2 , 4-bis ( 4-hydroxyphengl )-1 , 3- cyclobutane dicarboxglic aicd ( 9 ) , ( Z )-p-hydroxy cinamic acid (10) , ( E )-p-hydroxy cinamic acid (11) , vanillic acid ( 12 ) , 2α, 3β-dihydroxyurs-5 , 12-dien-28-oic acid ( 13 ) , 2α, 3β, 23-trihydroxyurs-12- en-28-oic acid (14) , andβ-stiosterol (15) . Compounds 1 - 4 , and 8 - 14 were isolated from the titled plant for the first time . In addition , compounds 1 - 3 may have closed relationships with the effects of analgesic .

Key words: Craibiodendron yunnanense

摘要：

从金叶子(Craibiodendron yunnanense W . W . Smith) 叶部分的70%丙酮提取液中共分离得15 个化合物, 分别鉴定为: asebotoxin-III ( 1) , grayanotoxin-XVIII ( 2) , leucothol A ( 3 ) ,proA-4 (4) , 槲皮素-3-O-β-半乳吡喃糖苷(5) , 槲皮素-3-O-α-阿拉伯呋喃糖苷(6) , 槲皮素-3-O-α-鼠李吡喃糖苷( 7) , 山奈酚-3-O-α-鼠李吡喃糖苷( 8 ) , 2 , 4-bis ( 4-hydroxyphengl ) -1 , 3-cyclobutane dicarboxglic aicd (9) , ( Z )-对羟基桂皮酸(10) , ( E )-对羟基桂皮酸( 11) , 香草酸(12) , 2α, 3β-dihydroxyurs-5 , 12-dien-28-oic acid (13) , 2α, 3β, 23-trihydroxyurs-12- en-28-oic acid (14) 和β-谷甾醇(15)。化合物1～4 , 8～14 为首次从该种植物中得到。其中木藜芦烷类二萜asebotoxin-III ( 1) 为主成分之一, 我们推测化合物1 和其余两个木藜芦烷类二萜grayanotoxin-XVIII (2 ) , leucothol A (3) 为金叶子的活性成分, 可能与该植物具有活络止痛的药效有密切的关系。

关键词: 金叶子, 杜鹃花科, 化学成分, 木藜芦烷类二萜FONT