Integrative Biology Journals

Natural Products and Bioprospecting ›› 2018, Vol. 8 ›› Issue (1): 31-35.DOI: 10.1007/s13659-017-0146-6

• ORIGINAL ARTICLES • Previous Articles     Next Articles

Anemhupehins A-C, Podocarpane Diterpenoids from Anemone hupehensis

Xing Yu, Kai-Ting Duan, Zhen-Xiong Wang, He-Ping Chen, Xiao-Qing Gan, Rong Huang, Zheng-Hui Li, Tao Feng, Ji-Kai Liu   

  1. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China
  • Received:2017-10-22 Revised:2017-11-21 Online:2018-02-27 Published:2018-02-24
  • Contact: Tao Feng, Ji-Kai Liu

Anemhupehins A-C, Podocarpane Diterpenoids from Anemone hupehensis

Xing Yu, Kai-Ting Duan, Zhen-Xiong Wang, He-Ping Chen, Xiao-Qing Gan, Rong Huang, Zheng-Hui Li, Tao Feng, Ji-Kai Liu   

  1. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China
  • 基金资助:
    This work was financially supported by National Natural Science Foundation of China (81561148013, 81373289, and 21502239), the Key Projects of Technological Innovation of Hubei Province (No. 2016ACA138), and the Fundamental Research Funds for the Central University, South-Central University for Nationalities (CZZ17006, CSP17061). The authors thank Analytical & Measuring Centre, South-Central University for Nationalities, for the NMR measurements.

Abstract: Three new podocarpane diterpenoids, namely anemhupehins A-C (1-3), together with four known analogues (4-7), have been isolated from aerial parts of Anemone hupehensis. Their structures were characterized based on extensive spectroscopic data. Compounds 1 and 4 showed certain cytotoxicities against human cancer cell lines.

Key words: Anemone hupehensis, Podocarpane diterpenoids, Cytotoxicity

摘要: Three new podocarpane diterpenoids, namely anemhupehins A-C (1-3), together with four known analogues (4-7), have been isolated from aerial parts of Anemone hupehensis. Their structures were characterized based on extensive spectroscopic data. Compounds 1 and 4 showed certain cytotoxicities against human cancer cell lines.

关键词: Anemone hupehensis, Podocarpane diterpenoids, Cytotoxicity