Monoterpenoid indole alkaloids from Alstonia rostrata

doi:10.1007/s13659-012-0019-y

Natural Products and Bioprospecting ›› 2012, Vol. 2 ›› Issue (3): 121-125.DOI: 10.1007/s13659-012-0019-y

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Monoterpenoid indole alkaloids from Alstonia rostrata

Mei-Fen BAO^a,c, Chun-Xia ZENG^b, Yan QU^a, Ling-Mei KONG^a, Ya-Ping LIU^a, Xiang-Hai CAI^a, Xiao-Dong LUO^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Southwest China Germplasm Bank of Wild Species, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
c Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Received:2012-03-05 Revised:2012-04-09 Online:2018-02-11 Published:2012-06-24
Supported by:
This project was supported by the National Natural Science Foundation of China(21172225, 31170334), the 973 Program of Ministry of Science and Technology of China(2009CB522300), the XiBuZhiGuang Project of Chinese Academy of Sciences, and the Young Academic and Technical Leader Raising Foundation of Yunnan Province(No. 2010CI049).

Monoterpenoid indole alkaloids from Alstonia rostrata

Mei-Fen BAO^a,c, Chun-Xia ZENG^b, Yan QU^a, Ling-Mei KONG^a, Ya-Ping LIU^a, Xiang-Hai CAI^a, Xiao-Dong LUO^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Southwest China Germplasm Bank of Wild Species, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
c Graduate University of Chinese Academy of Sciences, Beijing 100049, China

通讯作者: Xiang-Hai CAI,E-mail:xhcai@mail.kib.ac.cn;Xiao-Dong LUO,E-mail:xdluo@mail.kib.ac.cn
基金资助:
This project was supported by the National Natural Science Foundation of China(21172225, 31170334), the 973 Program of Ministry of Science and Technology of China(2009CB522300), the XiBuZhiGuang Project of Chinese Academy of Sciences, and the Young Academic and Technical Leader Raising Foundation of Yunnan Province(No. 2010CI049).

Abstract

Abstract: Four new monoterpenoid indole alkaloids, alstrostines C-F together with thirteen known alkaloids were isolated from the leaves and twigs of Alstonia rostrata. All structures of new compounds were elucidated based on NMR, FTIR, UV, and MS spectroscopic data. Alstrostines C-E might originate from keto-enol tautomerism of preakummicine during biogenetic pathway of akummicine.

Key words: monoterpenoid indole alkaloid, alstrostines C-F, Alstonia rostrata, Apocynaceae

摘要： Four new monoterpenoid indole alkaloids, alstrostines C-F together with thirteen known alkaloids were isolated from the leaves and twigs of Alstonia rostrata. All structures of new compounds were elucidated based on NMR, FTIR, UV, and MS spectroscopic data. Alstrostines C-E might originate from keto-enol tautomerism of preakummicine during biogenetic pathway of akummicine.

关键词: monoterpenoid indole alkaloid, alstrostines C-F, Alstonia rostrata, Apocynaceae

Mei-Fen BAO, Chun-Xia ZENG, Yan QU, Ling-Mei KONG, Ya-Ping LIU, Xiang-Hai CAI, Xiao-Dong LUO. Monoterpenoid indole alkaloids from Alstonia rostrata[J]. Natural Products and Bioprospecting, 2012, 2(3): 121-125.

Mei-Fen BAO, Chun-Xia ZENG, Yan QU, Ling-Mei KONG, Ya-Ping LIU, Xiang-Hai CAI, Xiao-Dong LUO. Monoterpenoid indole alkaloids from Alstonia rostrata[J]. 应用天然产物, 2012, 2(3): 121-125.

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Monoterpenoid indole alkaloids from Alstonia rostrata

Monoterpenoid indole alkaloids from Alstonia rostrata

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