Triterpenoid alkaloid derivatives from Buxus rugulosa

doi:10.1007/s13659-011-0010-z

Natural Products and Bioprospecting ›› 2011, Vol. 1 ›› Issue (2): 71-74.DOI: 10.1007/s13659-011-0010-z

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Triterpenoid alkaloid derivatives from Buxus rugulosa

Yu-Xin YAN^a,b, Lin ZHOU^a, Yun SUN^a, Jian-Chao CHEN^a, Jia SU^a, Yan LI^a, Ming-Hua QIU^a,b

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100039, China

Received:2011-08-04 Revised:2011-09-04 Online:2017-11-24 Published:2011-04-24
Supported by:
The project was financially supported by the Knowledge Innovation Program of the CAS(Grant No. KSCX2-YW-G-038, KSCX2-YW-R-194, KSCX2-EW-R-15, and KZCX2-XB2-15-03), as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China(P2008-ZZ05 and P2010-ZZ14).

Triterpenoid alkaloid derivatives from Buxus rugulosa

Yu-Xin YAN^a,b, Lin ZHOU^a, Yun SUN^a, Jian-Chao CHEN^a, Jia SU^a, Yan LI^a, Ming-Hua QIU^a,b

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b Graduate University of Chinese Academy of Sciences, Beijing 100039, China

通讯作者: Ming-Hua QIU,E-mail:mhchiu@mail.kib.ac.cn
基金资助:
The project was financially supported by the Knowledge Innovation Program of the CAS(Grant No. KSCX2-YW-G-038, KSCX2-YW-R-194, KSCX2-EW-R-15, and KZCX2-XB2-15-03), as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China(P2008-ZZ05 and P2010-ZZ14).

Abstract

Abstract: Four new triterpenoid alkaloid derivatives, buxrugulines A-D(1-4), together with four known ones(5-8), were isolated from the leaves and stems of Buxus rugulosa. The structures of compounds 1-4 were elucidated by NMR and MS spectroscopic analysis. All compounds were assayed for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, and SW480 cells lines.

Key words: Buxus rugulosa, triterpenoid alkaloid derivatives, buxruguline, cytotoxicity

摘要： Four new triterpenoid alkaloid derivatives, buxrugulines A-D(1-4), together with four known ones(5-8), were isolated from the leaves and stems of Buxus rugulosa. The structures of compounds 1-4 were elucidated by NMR and MS spectroscopic analysis. All compounds were assayed for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, and SW480 cells lines.

关键词: Buxus rugulosa, triterpenoid alkaloid derivatives, buxruguline, cytotoxicity

Yu-Xin YAN, Lin ZHOU, Yun SUN, Jian-Chao CHEN, Jia SU, Yan LI, Ming-Hua QIU. Triterpenoid alkaloid derivatives from Buxus rugulosa[J]. Natural Products and Bioprospecting, 2011, 1(2): 71-74.

Yu-Xin YAN, Lin ZHOU, Yun SUN, Jian-Chao CHEN, Jia SU, Yan LI, Ming-Hua QIU. Triterpenoid alkaloid derivatives from Buxus rugulosa[J]. 应用天然产物, 2011, 1(2): 71-74.

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Triterpenoid alkaloid derivatives from Buxus rugulosa

Triterpenoid alkaloid derivatives from Buxus rugulosa

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