Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus

doi:10.1007/s13659-014-0030-6

Natural Products and Bioprospecting ›› 2014, Vol. 4 ›› Issue (4): 221-225.DOI: 10.1007/s13659-014-0030-6

• Original article • Previous Articles Next Articles

Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus

Fei Liu^1,2, Yu-Cheng Liu^1,2, Wei-Wei Jiang^1,2, Juan He¹, Xing-De Wu¹, Li-Yan Peng¹, Jia Su¹, Xiao Cheng¹, Qin-Shi Zhao¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, People's Republic of China;
2. University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China

Received:2014-05-27 Revised:2014-06-23 Online:2018-02-11 Published:2014-08-24
Supported by:
This work was financially supported by the National Natural Science Foundation of China(No. U0932602) and the National Basic Research Program of China(973 Program No. 2011CB915503).

Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus

Fei Liu^1,2, Yu-Cheng Liu^1,2, Wei-Wei Jiang^1,2, Juan He¹, Xing-De Wu¹, Li-Yan Peng¹, Jia Su¹, Xiao Cheng¹, Qin-Shi Zhao¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, People's Republic of China;
2. University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China

通讯作者: Qin-Shi Zhao,e-mail:qinshizhao@mail.kib.ac.cn
基金资助:
This work was financially supported by the National Natural Science Foundation of China(No. U0932602) and the National Basic Research Program of China(973 Program No. 2011CB915503).

Abstract

Abstract: Carinatine A(1), a C₁₆N₂-type Lycopodium alkaloid possessing a 5/6/6/6 ring system formed by a new C-4/C-12 bond, and carinatine B(2), the first derivative of lycojaponicumin C, along 16 known compounds, were isolated from the whole plant of Phlegmariurus carinatus. Their structures were elucidated based on the spectroscopic data. The two new isolates were no inhibitory activity for the acetylcholinesterase(AChE).

Key words: Lycopodium alkaloid, Phlegmariurus carinatus, Carinatines A and B, Acetylcholinesterase (AChE) inhibitory activity

摘要： Carinatine A(1), a C₁₆N₂-type Lycopodium alkaloid possessing a 5/6/6/6 ring system formed by a new C-4/C-12 bond, and carinatine B(2), the first derivative of lycojaponicumin C, along 16 known compounds, were isolated from the whole plant of Phlegmariurus carinatus. Their structures were elucidated based on the spectroscopic data. The two new isolates were no inhibitory activity for the acetylcholinesterase(AChE).

关键词: Lycopodium alkaloid, Phlegmariurus carinatus, Carinatines A and B, Acetylcholinesterase (AChE) inhibitory activity

Fei Liu, Yu-Cheng Liu, Wei-Wei Jiang, Juan He, Xing-De Wu, Li-Yan Peng, Jia Su, Xiao Cheng, Qin-Shi Zhao. Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus[J]. Natural Products and Bioprospecting, 2014, 4(4): 221-225.

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Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus

Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus

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