Abstract: Oligostilbenes have attracted much interest due to their intricate structures and diverse bioactivities. In this study, two stilbene dimers, (-)-7,8-cis-ε-viniferin (1) and carasiphenol A (2), and two trimers, suffruticosol A (3) and suffruticosol C (4), were investigated by electrospray ionization ion-trap time-of-flight multistage mass spectrometry (ESI-IT-TOF-MSⁿ). Based on the MSⁿ study, the fragmentation pathways and diagnostic ions of four oligostilbenes in both positive and negative modes were proposed. The consecutive elimination of phenol (C₆H₆O) and resorcinol (C₆H₆O₂) moieties were the particular dissociation for oligostilbenes due to the presence of 1,2-diphenylethylene nucleus. The present MSⁿ fragmentation study will provide valuable information for the fast characterization of oligostilbenes from complicated natural mixtures.

Key words: ESI-IT-TOF-MSⁿ, Fragmentation rules, Oligostilbenes

摘要： Oligostilbenes have attracted much interest due to their intricate structures and diverse bioactivities. In this study, two stilbene dimers, (-)-7,8-cis-ε-viniferin (1) and carasiphenol A (2), and two trimers, suffruticosol A (3) and suffruticosol C (4), were investigated by electrospray ionization ion-trap time-of-flight multistage mass spectrometry (ESI-IT-TOF-MSⁿ). Based on the MSⁿ study, the fragmentation pathways and diagnostic ions of four oligostilbenes in both positive and negative modes were proposed. The consecutive elimination of phenol (C₆H₆O) and resorcinol (C₆H₆O₂) moieties were the particular dissociation for oligostilbenes due to the presence of 1,2-diphenylethylene nucleus. The present MSⁿ fragmentation study will provide valuable information for the fast characterization of oligostilbenes from complicated natural mixtures.

关键词: ESI-IT-TOF-MSⁿ, Fragmentation rules, Oligostilbenes