Integrative Biology Journals
Natural Products and Bioprospecting

Natural Products and Bioprospecting ›› 2015, Vol. 5 ›› Issue (1): 23-28.DOI: 10.1007/s13659-014-0047-x

• Original article • Previous Articles     Next Articles

Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

Zhen-Zhu Zhao1,2, He-Ping Chen1,2, Tao Feng1, Zheng-Hui Li1, Ze-Jun Dong1, Ji-Kai Liu1   

  1. 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
    2. University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China
  • Received:2014-10-24 Revised:2014-11-18 Online:2018-02-11 Published:2015-02-24
  • Supported by:
    This work was financially supported by National Natural Science Foundation of China(U1132607, 81102346), and Natural Science Fund of Yunnan province(2011FB099).

Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens

Zhen-Zhu Zhao1,2, He-Ping Chen1,2, Tao Feng1, Zheng-Hui Li1, Ze-Jun Dong1, Ji-Kai Liu1   

  1. 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
    2. University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China
  • 通讯作者: Ji-Kai Liu,e-mail:jkliu@mail.kib.ac.cn
  • 基金资助:
    This work was financially supported by National Natural Science Foundation of China(U1132607, 81102346), and Natural Science Fund of Yunnan province(2011FB099).

PDF (PC)

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Abstract: Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol(1), 11-hydroxyacetoxydrim-7-en-3β-ol(2), 2, 6-dimethyl-7, 10-epoxy-10-hydroxymethyldodeca-2, 11-dien-6-ol(3), and 7, 10-epoxy-2, 6, 10-trimethyldodeca-2, 11-diene-4, 6-diol(4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1-4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities.

Key words: Phellinidium sulphurascens, Drimane, 7,10-Epoxy-2,6,10-trimethyldodeca-2,11-diene

摘要： Four new sesquiterpenoids, namely 12-hydroxy-3-oxodrimenol(1), 11-hydroxyacetoxydrim-7-en-3β-ol(2), 2, 6-dimethyl-7, 10-epoxy-10-hydroxymethyldodeca-2, 11-dien-6-ol(3), and 7, 10-epoxy-2, 6, 10-trimethyldodeca-2, 11-diene-4, 6-diol(4), along with fourteen known compounds, were isolated from the cultures of Phellinidium sulphurascens. The structures of compounds 1-4 were established on the basis of extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities.

关键词: Phellinidium sulphurascens, Drimane, 7,10-Epoxy-2,6,10-trimethyldodeca-2,11-diene

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