New Lycopodium alkaloids from Lycopodium obscurum

doi:10.1007/s13659-013-0015-x

应用天然产物 ›› 2013, Vol. 3 ›› Issue (2): 52-55.DOI: 10.1007/s13659-013-0015-x

New Lycopodium alkaloids from Lycopodium obscurum

Xue-Yuan ZHANG^a,b, Liao-Bin DONG^a,b, Fei LIU^a,b, Xing-De WU^a, Juan HE^a, Li-Yan PENG^a, Huai-Rong LUO^a, Qin-Shi ZHAO^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b University of Chinese Academy of Sciences, Beijing 100049, China

收稿日期:2013-02-19 修回日期:2013-03-17 出版日期:2013-04-24 发布日期:2018-02-11
通讯作者: Qin-Shi ZHAO,E-mail:qinshizhao@mail.kib.ac.cn
基金资助:
This work was financially supported by the National Basic Research Program of China (973 Program Nos. 2011CB915503 and 2009CB522303) and the National Natural Science Foundation of China (Nos. U0932602 and 90813004).

New Lycopodium alkaloids from Lycopodium obscurum

Xue-Yuan ZHANG^a,b, Liao-Bin DONG^a,b, Fei LIU^a,b, Xing-De WU^a, Juan HE^a, Li-Yan PENG^a, Huai-Rong LUO^a, Qin-Shi ZHAO^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b University of Chinese Academy of Sciences, Beijing 100049, China

Received:2013-02-19 Revised:2013-03-17 Online:2013-04-24 Published:2018-02-11
Supported by:
This work was financially supported by the National Basic Research Program of China (973 Program Nos. 2011CB915503 and 2009CB522303) and the National Natural Science Foundation of China (Nos. U0932602 and 90813004).

摘要/Abstract

摘要： Three new Lycopodium alkaloids, obscurumines C-E (1-3), along with nine known compounds, were isolated from the club moss Lycopodium obscurum L. Structures of the new compounds were determined on the basis of their spectroscopic analysis and the relative configurations of 1 were established by X-ray crystallographic analysis. All the new isolates were tested for the acetylcholinesterase (AChE) inhibitory activity.

关键词: obscurumines, Lydopodium alkaloids, Lycopodium obscurum, acetylcholinesterase (AChE) inhibitory activity

Abstract: Three new Lycopodium alkaloids, obscurumines C-E (1-3), along with nine known compounds, were isolated from the club moss Lycopodium obscurum L. Structures of the new compounds were determined on the basis of their spectroscopic analysis and the relative configurations of 1 were established by X-ray crystallographic analysis. All the new isolates were tested for the acetylcholinesterase (AChE) inhibitory activity.

Key words: obscurumines, Lydopodium alkaloids, Lycopodium obscurum, acetylcholinesterase (AChE) inhibitory activity

Xue-Yuan ZHANG, Liao-Bin DONG, Fei LIU, Xing-De WU, Juan HE, Li-Yan PENG, Huai-Rong LUO, Qin-Shi ZHAO. New Lycopodium alkaloids from Lycopodium obscurum[J]. 应用天然产物, 2013, 3(2): 52-55.

Xue-Yuan ZHANG, Liao-Bin DONG, Fei LIU, Xing-De WU, Juan HE, Li-Yan PENG, Huai-Rong LUO, Qin-Shi ZHAO. New Lycopodium alkaloids from Lycopodium obscurum[J]. Natural Products and Bioprospecting, 2013, 3(2): 52-55.

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New Lycopodium alkaloids from Lycopodium obscurum

New Lycopodium alkaloids from Lycopodium obscurum

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