整合生物学期刊网

应用天然产物 ›› 2021, Vol. 11 ›› Issue (1): 119-126.DOI: 10.1007/s13659-020-00285-7

• ORIGINAL ARTICLES • 上一篇    下一篇

3,4-Secocycloartane Triterpenoids from the Cones of Pseudolarix amabilis

Si-Jia Xiao1, Bo Li1,2, Zheng-Rui Huang3, Wen-Lin Yuan1, Ji Ye1, Hui-Liang Li1, Xi-Ke Xu1, Yun-Heng Shen1, Wei-Dong Zhang1,2   

  1. 1 Department of Phytochemistry, School of Pharmacy, Naval Medical University(Second Military Medical University), Shanghai 200433, China;
    2 State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai 201203, China;
    3 Department of Applied Chemistry, Xi'an University of Technology, Xi'an 710048, China
  • 收稿日期:2020-10-09 修回日期:2020-11-09 出版日期:2021-02-24 发布日期:2021-03-11
  • 通讯作者: Yun-Heng Shen, Wei-Dong Zhang
  • 基金资助:
    The work was supported by NSFC (31870327, 81230090, 81520108030, 1302658), National Major Project of China (2018ZX09731016-005), The Key Research and Development Program of China (2017YFC1702002, 2017YFC1700200), Professor of Chang Jiang Scholars Program, Scientific Foundation of Shanghai China (17431902800, 16401901300), Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300).

3,4-Secocycloartane Triterpenoids from the Cones of Pseudolarix amabilis

Si-Jia Xiao1, Bo Li1,2, Zheng-Rui Huang3, Wen-Lin Yuan1, Ji Ye1, Hui-Liang Li1, Xi-Ke Xu1, Yun-Heng Shen1, Wei-Dong Zhang1,2   

  1. 1 Department of Phytochemistry, School of Pharmacy, Naval Medical University(Second Military Medical University), Shanghai 200433, China;
    2 State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai 201203, China;
    3 Department of Applied Chemistry, Xi'an University of Technology, Xi'an 710048, China
  • Received:2020-10-09 Revised:2020-11-09 Online:2021-02-24 Published:2021-03-11
  • Contact: Yun-Heng Shen, Wei-Dong Zhang
  • Supported by:
    The work was supported by NSFC (31870327, 81230090, 81520108030, 1302658), National Major Project of China (2018ZX09731016-005), The Key Research and Development Program of China (2017YFC1702002, 2017YFC1700200), Professor of Chang Jiang Scholars Program, Scientific Foundation of Shanghai China (17431902800, 16401901300), Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products (10DZ2251300).

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摘要： Four new 3,4-secocycloartane triterpenoids, pseudolactones A-D (1-4), were isolated from the ethanol extract of the cones of Pseudol arixamabilis. Their structures were established by extensive 1D- and 2D-NMR experiments. The cones of P. arixamabilis are enriched in the ring-expanded or cleaved cycloartane triterpenoids. This work provides new insight into cycloartane triterpenoids from the cones of P. arixamabilis.

关键词: Pseudol arixamabilis, Triterpenoids, 3,4-Secocycloartane, Pseudolactones A-D

Abstract: Four new 3,4-secocycloartane triterpenoids, pseudolactones A-D (1-4), were isolated from the ethanol extract of the cones of Pseudol arixamabilis. Their structures were established by extensive 1D- and 2D-NMR experiments. The cones of P. arixamabilis are enriched in the ring-expanded or cleaved cycloartane triterpenoids. This work provides new insight into cycloartane triterpenoids from the cones of P. arixamabilis.

Key words: Pseudol arixamabilis, Triterpenoids, 3,4-Secocycloartane, Pseudolactones A-D

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