整合生物学期刊网

应用天然产物 ›› 2019, Vol. 9 ›› Issue (4): 279-286.DOI: 10.1007/s13659-019-0212-3

• ORIGINAL ARTICLES • 上一篇    下一篇

A Fragmentation Study on Four Oligostilbenes by Electrospray Tandem Mass Spectrometry

Chen-Chen Zhang1,2,3, Chang-An Geng1,2, Ji-Jun Chen1,2,3   

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Kunming 650201, Yunnan, People's Republic of China;
    2 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, People's Republic of China;
    3 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China
  • 收稿日期:2019-04-23 修回日期:2019-05-14 出版日期:2019-08-24 发布日期:2019-08-09
  • 通讯作者: Chang-An Geng, Ji-Jun Chen
  • 基金资助:
    This work was financially supported by the National Natural Science Foundation of China (81773609), the Program of Yunling Scholarship, and the Applied Basic Research Programs of Yunnan Province (2017FB137).

A Fragmentation Study on Four Oligostilbenes by Electrospray Tandem Mass Spectrometry

Chen-Chen Zhang1,2,3, Chang-An Geng1,2, Ji-Jun Chen1,2,3   

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, 132# Lanhei Road, Kunming 650201, Yunnan, People's Republic of China;
    2 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, People's Republic of China;
    3 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China
  • Received:2019-04-23 Revised:2019-05-14 Online:2019-08-24 Published:2019-08-09
  • Contact: Chang-An Geng, Ji-Jun Chen
  • Supported by:
    This work was financially supported by the National Natural Science Foundation of China (81773609), the Program of Yunling Scholarship, and the Applied Basic Research Programs of Yunnan Province (2017FB137).

PDF (PC)

10810

摘要： Oligostilbenes have attracted much interest due to their intricate structures and diverse bioactivities. In this study, two stilbene dimers, (-)-7,8-cis-ε-viniferin (1) and carasiphenol A (2), and two trimers, suffruticosol A (3) and suffruticosol C (4), were investigated by electrospray ionization ion-trap time-of-flight multistage mass spectrometry (ESI-IT-TOF-MSn). Based on the MSn study, the fragmentation pathways and diagnostic ions of four oligostilbenes in both positive and negative modes were proposed. The consecutive elimination of phenol (C6H6O) and resorcinol (C6H6O2) moieties were the particular dissociation for oligostilbenes due to the presence of 1,2-diphenylethylene nucleus. The present MSn fragmentation study will provide valuable information for the fast characterization of oligostilbenes from complicated natural mixtures.

关键词: ESI-IT-TOF-MSn, Fragmentation rules, Oligostilbenes

Abstract: Oligostilbenes have attracted much interest due to their intricate structures and diverse bioactivities. In this study, two stilbene dimers, (-)-7,8-cis-ε-viniferin (1) and carasiphenol A (2), and two trimers, suffruticosol A (3) and suffruticosol C (4), were investigated by electrospray ionization ion-trap time-of-flight multistage mass spectrometry (ESI-IT-TOF-MSn). Based on the MSn study, the fragmentation pathways and diagnostic ions of four oligostilbenes in both positive and negative modes were proposed. The consecutive elimination of phenol (C6H6O) and resorcinol (C6H6O2) moieties were the particular dissociation for oligostilbenes due to the presence of 1,2-diphenylethylene nucleus. The present MSn fragmentation study will provide valuable information for the fast characterization of oligostilbenes from complicated natural mixtures.

Key words: ESI-IT-TOF-MSn, Fragmentation rules, Oligostilbenes

版权所有 © 《应用天然产物》编辑部
地址：132# Lanhei Road, Heilongtan, Kunming 650201, Yunnan, China　
电话：0871-65223223　
E-mail：npb@mail.kib.ac.cn
技术支持：北京玛格泰克科技发展有限公司