Untiring Researches for Alternative Resources of Rhizoma Paridis

doi:10.1007/s13659-018-0179-5

应用天然产物 ›› 2018, Vol. 8 ›› Issue (4): 265-278.DOI: 10.1007/s13659-018-0179-5

Untiring Researches for Alternative Resources of Rhizoma Paridis

Xu-Jie Qin, Wei Ni, Chang-Xiang Chen, Hai-Yang Liu

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming 650201, People's Republic of China

收稿日期:2018-04-18 修回日期:2018-07-02 出版日期:2018-08-24 发布日期:2018-08-28
通讯作者: Hai-Yang Liu,haiyangliu@mail.kib.ac.cn
基金资助:
This work was financially supported by the National Natural Science Foundation of China (Nos. 31570363, 31770391, and 31600283), the Natural Science Foundation of Yunnan Province (2015FA031 and 2017FB128), the Science and Technology Research Program (Grant No. KIB2016001) of Kunming Institute of Botany, CAS, Guiding Program of Interdisciplinary Studies from Kunming Institute of Botany, CAS (Grant No. KIB2017004), and the Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China (P2017-ZZ04), Kunming Institute of Botany, Chinese Academy of Sciences.

Untiring Researches for Alternative Resources of Rhizoma Paridis

Xu-Jie Qin, Wei Ni, Chang-Xiang Chen, Hai-Yang Liu

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Medicinal Chemistry, Kunming 650201, People's Republic of China

Received:2018-04-18 Revised:2018-07-02 Online:2018-08-24 Published:2018-08-28
Contact: Hai-Yang Liu,haiyangliu@mail.kib.ac.cn
Supported by:
This work was financially supported by the National Natural Science Foundation of China (Nos. 31570363, 31770391, and 31600283), the Natural Science Foundation of Yunnan Province (2015FA031 and 2017FB128), the Science and Technology Research Program (Grant No. KIB2016001) of Kunming Institute of Botany, CAS, Guiding Program of Interdisciplinary Studies from Kunming Institute of Botany, CAS (Grant No. KIB2017004), and the Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China (P2017-ZZ04), Kunming Institute of Botany, Chinese Academy of Sciences.

摘要/Abstract

摘要： Rhizoma Paridis (RP, 重楼), a traditional Chinese medicine, is the rhizoma of Paris polyphylla var. yunnanensis (PPY) or P. polyphylla var. chinensis which are widely used as important raw materials for several Chinese patent drugs. However, the wild resources of these herbs have become less and less due to their slow-growing characteristics and previously excessive excavation. This review covers untiring investigations on alternative resources of RP by our research group over the past decades, including non-medicinal parts of PPY as well as other plants of Liliaceae and Liliflorae families. The arial parts of PPY and the whole plants of Trillium kamtschaticum might be alternative resources for RP based on the fact that they shared the same or similar saponins and bioactivities.

关键词: Rhizoma Paridis, Paris polyphylla, Alternative resources, Steroidal saponins, Bioactivities

Abstract: Rhizoma Paridis (RP, 重楼), a traditional Chinese medicine, is the rhizoma of Paris polyphylla var. yunnanensis (PPY) or P. polyphylla var. chinensis which are widely used as important raw materials for several Chinese patent drugs. However, the wild resources of these herbs have become less and less due to their slow-growing characteristics and previously excessive excavation. This review covers untiring investigations on alternative resources of RP by our research group over the past decades, including non-medicinal parts of PPY as well as other plants of Liliaceae and Liliflorae families. The arial parts of PPY and the whole plants of Trillium kamtschaticum might be alternative resources for RP based on the fact that they shared the same or similar saponins and bioactivities.

Key words: Rhizoma Paridis, Paris polyphylla, Alternative resources, Steroidal saponins, Bioactivities

Xu-Jie Qin, Wei Ni, Chang-Xiang Chen, Hai-Yang Liu. Untiring Researches for Alternative Resources of Rhizoma Paridis[J]. 应用天然产物, 2018, 8(4): 265-278.

Xu-Jie Qin, Wei Ni, Chang-Xiang Chen, Hai-Yang Liu. Untiring Researches for Alternative Resources of Rhizoma Paridis[J]. Natural Products and Bioprospecting, 2018, 8(4): 265-278.

参考文献

1. H. Li, The Genus Paris (Trilliaceae) (Science Press, Beijing, 1998), pp. 12-16
2. Y.H. Ji, P.W. Fritsch, H. Li, T.J. Xiao, Z.K. Zhou, Ann. Bot. 98, 245-256 (2006)
3. H. Li, L.G. Lei, Y.M. Yang, J. West China For. Sci. 46, 1-5 (2017)
4. Y.H. Ji, C.J. Yang, Y.L. Huang, Phytotaxa 306, 234-236 (2017)
5. Z. Wang, X.Z. Cai, Z.X. Zhong, Z. Xu, N. Wei, J.F. Xie, G.W. Hu, Q.F. Wang, Phytotaxa 314, 145-149 (2017)
6. Y.Y. Liu, D.D. Luo, H. Yao, X.C. Zhang, L.W. Yang, B.Z. Duan, Phytotaxa 326, 297-300 (2017)
7. J. Yang, Y.H. Wang, H. Li, Phytotaxa 329, 193-196 (2017)
8. Chinese Pharmacopoeia Commission, Pharmacopoeia of the People's Republic of China, vol. 1 (China Medical Science Press, Beijing, 2010), pp. 243-244
9. T. Nohara, H. Yabuta, M. Suenobu, R. Hida, K. Miyahara, T. Kawasaki, Chem. Pharm. Bull. 21, 1240-1247 (1973)
10. S.B. Singh, R.S. Thakur, H.R. Schulten, Phytochemistry 21, 2925-2929 (1980)
11. C.X. Chen,Y.T.Zhang, J.Zhou,Acta Bot.Yunnanica 5, 91-97(1983)
12. J.Y. Zhang, Y.Z. Wang, Y.L. Zhao, S.B. Yang, Z.T. Zuo, M.Q. Yang, J. Zhang, W.Z. Yang, T.-M. Yang, H. Jin, J. Asian Nat. Prod. Res. 13, 670-681 (2011)
13. Y. Mimaki, M. Kuroda, Y. Obata, Y. Sashida, M. Kitahara, A. Yasuda, N. Naoi, Z.W. Xu, M.R. Li, A.N. Lao, Nat. Prod. Lett. 14, 357-364 (2000)
14. Y. Zhao, L.P. Kang, Y.X. Liu, Y.G. Liang, D.W. Tan, Z.Y. Yu, Y.W. Cong, B.P. Ma, Planta Med. 75, 356-363 (2009)
15. X. Wu, L. Wang, H. Wang, Y. Dai, W.C. Ye, Y.L. Li, Phytochemistry 81, 133-143 (2012)
16. L.P. Kang, Y.X. Liu, T. Eichhorn, E. Dapat, H.S. Yu, Y. Zhao, C. Q. Xiong, C. Liu, T. Efferth, B.P. Ma, J. Nat. Prod. 75, 1201-1205 (2012)
17. Y.S. Chen, Y. He, C. Chen, Y. Zeng, D. Xue, F.Y. Wen, L. Wang, H. Zhang, J.R. Du, Steroids 83, 39-44 (2014)
18. F.Y. Long, Y.S. Chen, L. Zhang, X. Kuang, Y. Yu, L.F. Wang, X. J. Liu, L. Wang, Y.F. Zhou, N. Sang, J.R. Du, J. Ethnopharmacol. 162, 112-120 (2015)
19. Y.S. Wen, W. Ni, X.J. Qin, H. Yan, C.X. Chen, Y. Hua, Y.C. Cheng, L. He, H.Y. Liu, Phytochem. Lett. 12, 31-34 (2015)
20. S.S. Jing, Y. Wang, X. Li, S.L. Man, W.Y. Gao, Nat. Prod. Res. 31, 660-666 (2017)
21. D.W. Deng, D.R. Lauren, J.M. Cooney, D.J. Jensen, K.V. Wurms, J.E. Upritchard, R.D. Cannon, M.Z. Wang, M.Z. Li, Planta Med. 74, 1397-1402 (2008)
22. L.C. Zhu, J. Tan, B.C. Wang, L.H. Guan, Y.P. Liu, C. Zheng, Iran. J. Pharm. Res. 10, 279-286 (2011)
23. J.C.N. Ma, F.W. Lau, Phytochemistry 24, 1561-1565 (1985)
24. Y.L. Fu, Z.Y. Yu, X.M. Tang, Y. Zhao, X.L. Yuan, S. Wang, B.P. Ma, Y.W. Cong, J. Thromb. Haemost. 6, 524-533 (2008)
25. X.J. Qin, D.J. Soun, W. Ni, C.X. Chen, Y. Hua, L. He, H.Y. Liu, Steroids 77, 1242-1248 (2012)
26. X.J. Qin, C.X. Chen, W. Ni, H. Yan, H.Y. Liu, Fitoterapia 84, 248-251 (2013)
27. X.J. Qin, M.Y. Yu, W. Ni, H. Yan, C.X. Chen, Y.C. Cheng, L. He, H.Y. Liu, Phytochemistry 121, 20-29 (2016)
28. C.X. Chen, J. Zhou, H. Nagasawa, A. Suzuki, Acta Bot. Yunnanica 17, 215-220 (1995)
29. C.X. Chen, J. Zhou, Acta Bot. Yunnanica 14, 111-113 (1992)
30. C.X. Chen, J. Zhou, Acta Bot. Yunnanica 6, 111-117 (1984)
31. C.X. Chen, J. Zhou, Acta Bot. Yunnanica 9, 239-245 (1987)
32. C.L. Sun, W. Ni, H. Yan, Z.H. Liu, L. Yang, Y.A. Si, Y. Hua, C. X. Chen, L. He, J.H. Zhao, H.Y. Liu, Steroids 92, 90-95 (2014)
33. L.Y. Jin, T.X. Lu, X.J. Qin, W. Ni, H. Yan, Y. Chen, H. Liu, H.P. He, H.Y. Liu, Nat. Prod. Bioprospect. 6, 205-210 (2016)
34. K.Z. Hou, Dictionary of the Families and Genera of Chinese Seed Plants, 2nd edn. (Science Press, Beijing, 1982), pp. 521-522
35. Jiangsu New Medicinal College, Dictionary of Traditional Chinese Materia Medica (Shanghai Scientific and Technological Press, Shanghai, 1977), p. 1841
36. Yunnan Food and Drug Administration, The Yunnan Chinese Materia Medica Standards ((Yi Nationality Medicine (Ⅲ)) (Yunnan Scientific and Technological Press, Kunming, 2010), pp. 5-6
37. B.B. Xie, H.Y. Liu, W. Ni, C.X. Chen, Y. Lü, L. Wu, Q.T. Zheng, Chem. Biodivers. 3, 1211-1218 (2006)
38. B.B. Xie, H.Y. Liu, W. Ni, C.X. Chen, Steroids 74, 950-955 (2009)
39. Y. Lu, C.X. Chen, W. Ni, Y. Hua, H.Y. Liu, Steroids 75, 982-987 (2010)
40. X.D. Zhang, C.X. Chen, J.Y. Yang, W. Ni, H.Y. Liu, Helv. Chim. Acta 95, 1087-1093 (2012)
41. T.X. Lu, T. Shu, X.J. Qin, W. Ni, Y.H. Ji, Q.R. Chen, A. Khan, Q. Zhao, H.Y. Liu, Steroids 123, 55-60 (2017)
42. B.B. Xie, C.X. Chen, Y.H. Guo, Y.Y. Li, Y.J. Liu, W. Ni, L.M. Yang, N.B. Gong, Y.T. Zheng, R.R. Wang, Y. Lü, H.Y. Liu, Planta Med. 79, 1063-1067 (2013)
43. H.Y. Liu, C.X. Chen, Y. Lu, J.Y. Yang, W. Ni, Nat. Prod. Bioprospect. 2, 11-15 (2012)
44. Y.A. Si, H. Yan, W. Ni, Z.H. Liu, T.X. Lu, C.X. Chen, H.Y. Liu, Nat. Prod. Bioprospect. 4, 315-318 (2014)
45. Y. Chen, Y.A. Si, H. Yan, X.J. Qin, C.X. Chen, H.Y. Liu, Nat. Prod. Bioprospect. 6, 173-182 (2016)
46. Y. Lu, B.B. Xie, C.X. Chen, W. Ni, Y. Hua, H.Y. Liu, Helv. Chim. Acta 94, 92-97 (2011)
47. F.C. Wang, J. Tang, X.Q. Chen, Z.Y. Zhang, L.K. Dai, S.Y. Liang, Y.C. Tang, L. Liu, K.Y. Lang, Flora of China, vol. 15 (Science Press, Beijing, 1978), pp. 97-98
48. Jiangsu New Medical College, Dictionary of Chinese Traditional Medicine (Zhong Yao Da Ci Dian) (Shanghai Science and Technology Press, Shanghai, 1986), pp. 831-975
49. M. Ono, C. Takamura, F. Sugita, C. Masuoka, H. Yoshimitsu, T. Ikeda, T. Nohara, Chem. Pharm. Bull. 55, 551-556 (2007)
50. A. Yokosuka, Y. Mimaki, Phytochemistry 69, 2724-2730 (2008)
51. Y. Chen, W. Ni, H. Yan, X.J. Qin, A. Khan, H. Liu, T. Shu, L.Y. Jin, H.Y. Liu, Phytochemistry 131, 165-173 (2016)
52. X.J. Qin, Y.A. Si, Y. Chen, H. Liu, W. Ni, H. Yan, T. Shu, Y.H. Ji, H.Y. Liu, Bioorg. Med. Chem. Lett. 27, 2267-2273 (2017)
53. Z.H. Liu, H. Yan, Y.A. Si, W. Ni, Y. Chen, L. He, H.Y. Liu, Steroids 106, 86-92 (2016)
54. H.Y. Liu, W. Ni, X.J. Hao, C.X. Chen, J. Asian Nat. Prod. Res. 8, 293-298 (2006)
55. L. Li, W. Ni, X.R. Li, Y. Hua, P.L. Fang, L.M. Kong, L.L. Pan, Y. Li, C.X. Chen, H.Y. Liu, Steroids 76, 1037-1042 (2011)
56. H.Y. Liu, C.X. Chen, Chin. Chem. Lett. 13, 633-636 (2002)
57. H.Y. Liu, W. Ni, B.B. Xie, L.Y. Zhou, X. Wang, C.X. Chen, Chem. Pharm. Bull. 54, 992-995 (2006)
58. J.Y. Yang, C.X. Chen, R.H. Zhao, X.J. Hao, H.Y. Liu, Nat. Prod. Res. 25, 40-44 (2011)
59. Z.H. Liu, H. Yan, Y.A. Si, W. Ni, Y. Chen, C.X. Chen, L. He, Z. Q. Zhang, H.Y. Liu, Fitoterapia 105, 210-214 (2015)
60. J.Y. Yang, R.H. Zhao, C.X. Chen, W. Ni, F. Teng, X.J. Hao, H.Y. Liu, Helv. Chim. Acta 91, 1077-1082 (2008)
61. X.J. Qin, W. Ni, C.X. Chen, H.Y. Liu, J. Ethnopharmacol. 224, 134-139 (2018)
62. C.X. Chen, J. Zhou, Y.T. Zhang, C.K. Gao, Acta Bot. Yunnanica 5, 219-223 (1983)
63. C.X. Chen, H.B. Lian, Y.C. Li, J. Zhou, Acta Bot. Yunnanica 12, 452 (1990)
64. C.X. Chen, J. Zhou, Y.T. Zhang, Y.Y. Zhao, Acta Bot. Yunnanica 12, 323-329 (1990)
65. C.X. Chen, Y.T. Zhang, J. Zhou, Acta Bot. Yunnanica 17, 473-478 (1995)
66. J. Zhou, C.X. Chen, R.M. Liu, C.R. Yang, Acta Bot. Sin. 25, 568-573 (1983)

[1]	Yue Zhao, Wen-Ke Gao, Xiang-Dong Wang, Li-Hua Zhang, Hai-Yang Yu, Hong-Hua Wu. Phytochemical and pharmacological studies on Solanum lyratum: a review[J]. 应用天然产物, 2022, 12(6): 39-39.
[2]	Mei-Ling Xiang, Bin-Yuan Hu, Zi-Heng Qi, Xiao-Na Wang, Tian-Zhen Xie, Zhao-Jie Wang, Dan-Yu Ma, Qi Zeng, Xiao-Dong Luo. Chemistry and bioactivities of natural steroidal alkaloids[J]. 应用天然产物, 2022, 12(4): 23-23.
[3]	Ke Ye, Hong-Lian Ai, Ji-Kai Liu. Identification and Bioactivities of Secondary Metabolites Derived from Endophytic Fungi Isolated from Ethnomedicinal Plants of Tujia in Hubei Province: A Review[J]. 应用天然产物, 2021, 11(2): 185-205.
[4]	Lin Wang, Junke Song, Ailin Liu, Bin Xiao, Sha Li, Zhang Wen, Yang Lu, Guanhua Du. Research Progress of the Antiviral Bioactivities of Natural Flavonoids[J]. 应用天然产物, 2020, 10(5): 271-283.
[5]	Hai-Li Yu, Qin Long, Wen-Fang Yi, Bao-Jia Yang, Yu Song, Xiao Ding, Shun-Lin Li, Xiao-Jiang Hao. Two New C21 Steroidal Glycosides from the Roots of Cynanchum paniculatum[J]. 应用天然产物, 2019, 9(3): 209-214.
[6]	Joseph Sakah Kaunda, Ying-Jun Zhang. The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review[J]. 应用天然产物, 2019, 9(2): 77-137.
[7]	Li-Wen Tian, Zhen Zhang, Hai-Lan Long, Ying-Jun Zhang. Steroidal Saponins from the Genus Smilax and Their Biological Activities[J]. 应用天然产物, 2017, 7(4): 283-298.
[8]	Ling-Yu Jin, Ting-Xiang Lu,. Xu-Jie Qin, Wei Ni, Huan Yan, Yu Chen, Hui Liu, Hong-Ping He, Hai-Yang Liu. Two New Highly Oxygenated Spirostanol Saponins from Paris polyphylla var. stenophylla[J]. 应用天然产物, 2016, 6(4): 205-210.
[9]	Xu-Jie Qin, Yun-Li Zhao, Chang-Wei Song, Bei Wang, Ying-Ying Chen, Lu Liu, Qiong Li, Dan Li, Ya-Ping Liu, Xiao-Dong Luo. Monoterpenoid Indole Alkaloids from Inadequately Dried Leaves of Alstonia scholaris[J]. 应用天然产物, 2015, 5(4): 185-193.
[10]	Muna Ali Abdalla, Josphat C. Matasyoh. Endophytes as Producers of Peptides: An Overview About the Recently Discovered Peptides from Endophytic Microbes[J]. 应用天然产物, 2014, 4(5): 257-270.
[11]	Da-Song YANG, Wei-Bing PENG, Zi-Lei LI, Xue WANG, Jian-Guo WEI, Ke-Chun LIU, Yong-Ping YANG, Xiao-Li LI. Chemical constituents from the aerial parts of Euphorbia sikkimensis and their bioactivities[J]. 应用天然产物, 2013, 3(3): 112-116.

Untiring Researches for Alternative Resources of Rhizoma Paridis

Untiring Researches for Alternative Resources of Rhizoma Paridis

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 11

编辑推荐

Metrics

本文评价