Steroidal Saponins from the Genus Smilax and Their Biological Activities

doi:10.1007/s13659-017-0139-5

应用天然产物 ›› 2017, Vol. 7 ›› Issue (4): 283-298.DOI: 10.1007/s13659-017-0139-5

• Review • 下一篇

Steroidal Saponins from the Genus Smilax and Their Biological Activities

Li-Wen Tian¹, Zhen Zhang¹, Hai-Lan Long¹, Ying-Jun Zhang²

1. School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

收稿日期:2017-04-16 修回日期:2017-06-12 出版日期:2017-08-24 发布日期:2018-02-07
通讯作者: Li-Wen Tian,e-mail:lwtian@smu.edu.cn
基金资助:
This work was financially supported by the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences (No. P2015-KF07), Science and Technology Program of Guangzhou, China (No. 201607010147), and Guangdong Medical Science Foundation (No. A2015225).

Steroidal Saponins from the Genus Smilax and Their Biological Activities

Li-Wen Tian¹, Zhen Zhang¹, Hai-Lan Long¹, Ying-Jun Zhang²

1. School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China;
2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

Received:2017-04-16 Revised:2017-06-12 Online:2017-08-24 Published:2018-02-07
Supported by:
This work was financially supported by the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences (No. P2015-KF07), Science and Technology Program of Guangzhou, China (No. 201607010147), and Guangdong Medical Science Foundation (No. A2015225).

摘要/Abstract

摘要： The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with diversified structure types, including spirostane, isospirostane, furostane, pregnane, and cholestane. This review mainly summarizes the steroidal saponins (1-104) reported from the genus Smilax between 1967 and 2016, and their biological activities. The relationship between structures of steroidal saponins and related biological activities were briefly discussed.

关键词: Smilax, Steroidal saponins, Biological activities

Abstract: The Smilax species, widely distributed in tropical region of the world and the warm areas of East Asia and North America, are extensively used as folk medicine to treat inflammatory disorders. Chemical investigation on Smilax species showed they are rich sources of steroidal saponins with diversified structure types, including spirostane, isospirostane, furostane, pregnane, and cholestane. This review mainly summarizes the steroidal saponins (1-104) reported from the genus Smilax between 1967 and 2016, and their biological activities. The relationship between structures of steroidal saponins and related biological activities were briefly discussed.

Key words: Smilax, Steroidal saponins, Biological activities

Li-Wen Tian, Zhen Zhang, Hai-Lan Long, Ying-Jun Zhang. Steroidal Saponins from the Genus Smilax and Their Biological Activities[J]. 应用天然产物, 2017, 7(4): 283-298.

Li-Wen Tian, Zhen Zhang, Hai-Lan Long, Ying-Jun Zhang. Steroidal Saponins from the Genus Smilax and Their Biological Activities[J]. Natural Products and Bioprospecting, 2017, 7(4): 283-298.

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Steroidal Saponins from the Genus Smilax and Their Biological Activities

Steroidal Saponins from the Genus Smilax and Their Biological Activities

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