Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

doi:10.1007/s13659-016-0093-7

应用天然产物 ›› 2016, Vol. 6 ›› Issue (3): 149-154.DOI: 10.1007/s13659-016-0093-7

• Original article • 下一篇

Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

Ling Ni^1,2, Xiu-Hong Zhong^1,2, Jie Cai³, Mei-Fen Bao^1,2, Bing-Jie Zhang¹, Jing Wu^1,2, Xiang-Hai Cai¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. University of Chinese Academy of Sciences, Beijing 100039, People's Republic of China;
3. Germplasm Bank of Wild Species in Southwest China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China

收稿日期:2016-01-22 修回日期:2016-03-13 出版日期:2016-06-24 发布日期:2018-02-08
通讯作者: Xiang-Hai Cai,e-mail:xhcai@mail.kib.ac.cn
基金资助:
This project was financially supported by the Young Academic and Technical Leader Raising Foundation of Yunnan Province (No.2010CI049)

Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

Ling Ni^1,2, Xiu-Hong Zhong^1,2, Jie Cai³, Mei-Fen Bao^1,2, Bing-Jie Zhang¹, Jing Wu^1,2, Xiang-Hai Cai¹

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2. University of Chinese Academy of Sciences, Beijing 100039, People's Republic of China;
3. Germplasm Bank of Wild Species in Southwest China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China

Received:2016-01-22 Revised:2016-03-13 Online:2016-06-24 Published:2018-02-08
Supported by:
This project was financially supported by the Young Academic and Technical Leader Raising Foundation of Yunnan Province (No.2010CI049)

摘要/Abstract

摘要： Five new alkaloids (1-5) were isolated from the leaves and twigs of Cephalotaxus lanceolata and C. fortunei var. alpina along with 24 known alkaloids. The new structures were elucidated based on spectroscopic data including 1D and 2D NMR, FTIR, UV and MS. These new alkaloids showed no cytotoxicity to HeLa, SGC-7901 gastric cancer, and A-549 lung cancer cell lines.

关键词: Cephalotaxus, Alkaloids, Cytotoxicity

Abstract: Five new alkaloids (1-5) were isolated from the leaves and twigs of Cephalotaxus lanceolata and C. fortunei var. alpina along with 24 known alkaloids. The new structures were elucidated based on spectroscopic data including 1D and 2D NMR, FTIR, UV and MS. These new alkaloids showed no cytotoxicity to HeLa, SGC-7901 gastric cancer, and A-549 lung cancer cell lines.

Key words: Cephalotaxus, Alkaloids, Cytotoxicity

Ling Ni, Xiu-Hong Zhong, Jie Cai, Mei-Fen Bao, Bing-Jie Zhang, Jing Wu, Xiang-Hai Cai. Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina[J]. 应用天然产物, 2016, 6(3): 149-154.

Ling Ni, Xiu-Hong Zhong, Jie Cai, Mei-Fen Bao, Bing-Jie Zhang, Jing Wu, Xiang-Hai Cai. Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina[J]. Natural Products and Bioprospecting, 2016, 6(3): 149-154.

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Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

Five New Alkaloids from Cephalotaxus lanceolata and C. fortunei var. alpina

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