Steroidal and pregnane glycosides from Ypsilandra thibetica

doi:10.1007/s13659-011-0039-z

应用天然产物 ›› 2012, Vol. 2 ›› Issue (1): 11-15.DOI: 10.1007/s13659-011-0039-z

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Steroidal and pregnane glycosides from Ypsilandra thibetica

Hai-Yang LIU, Chang-Xiang CHEN, Yi LU, Jun-Yun YANG, Wei NI

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

收稿日期:2011-11-27 修回日期:2011-12-26 出版日期:2012-02-24 发布日期:2018-02-11
通讯作者: Hai-Yang LIU,E-mail:haiyangliu@mail.kib.ac.cn
基金资助:
This work was financially supported by National Natural Science Funding of China(No. 31170333), the Natural Science Foundation of Yunnan Province(No. 2009CC019), the West Light Foundation of the Chinese Academy of Sciences(No. 2908025712W1), and a fund(No. 540806321211) of State Key Laboratory of Phytochemistry and Plant Resources in West China, Germplasm Bank of Wild Species and CAS Innovation Program of Kunming Institute of Botany.

Steroidal and pregnane glycosides from Ypsilandra thibetica

Hai-Yang LIU, Chang-Xiang CHEN, Yi LU, Jun-Yun YANG, Wei NI

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

Received:2011-11-27 Revised:2011-12-26 Online:2012-02-24 Published:2018-02-11
Supported by:
This work was financially supported by National Natural Science Funding of China(No. 31170333), the Natural Science Foundation of Yunnan Province(No. 2009CC019), the West Light Foundation of the Chinese Academy of Sciences(No. 2908025712W1), and a fund(No. 540806321211) of State Key Laboratory of Phytochemistry and Plant Resources in West China, Germplasm Bank of Wild Species and CAS Innovation Program of Kunming Institute of Botany.

摘要/Abstract

摘要： The whole plants of Ypsilandra thibetica have been analyzed as part of a systematic study on saponin constituents of medicinal plants. This has resulted in the isolation of two new bisdesmosidic furostanol saponins, named ypsilandroside P(1) and ypsilandroside Q(2), and one new pregnane glycoside, named ypsilandroside R(3), together with nine known steroidal glycosides. Their structures were elucidated on the basis of extensive spectroscopic analysis, including that of 2D NMR data, and the results of acidic hydrolysis. Ypsilandroside P(1) was cytotoxicity against two human tumor cell lines.

关键词: Ypsilandra thibetica, Liliaceae, furostanol glycoside, pregnane glycoside, ypsilandroside

Abstract: The whole plants of Ypsilandra thibetica have been analyzed as part of a systematic study on saponin constituents of medicinal plants. This has resulted in the isolation of two new bisdesmosidic furostanol saponins, named ypsilandroside P(1) and ypsilandroside Q(2), and one new pregnane glycoside, named ypsilandroside R(3), together with nine known steroidal glycosides. Their structures were elucidated on the basis of extensive spectroscopic analysis, including that of 2D NMR data, and the results of acidic hydrolysis. Ypsilandroside P(1) was cytotoxicity against two human tumor cell lines.

Key words: Ypsilandra thibetica, Liliaceae, furostanol glycoside, pregnane glycoside, ypsilandroside

Hai-Yang LIU, Chang-Xiang CHEN, Yi LU, Jun-Yun YANG, Wei NI. Steroidal and pregnane glycosides from Ypsilandra thibetica[J]. 应用天然产物, 2012, 2(1): 11-15.

Hai-Yang LIU, Chang-Xiang CHEN, Yi LU, Jun-Yun YANG, Wei NI. Steroidal and pregnane glycosides from Ypsilandra thibetica[J]. Natural Products and Bioprospecting, 2012, 2(1): 11-15.

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Steroidal and pregnane glycosides from Ypsilandra thibetica

Steroidal and pregnane glycosides from Ypsilandra thibetica

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