Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi

doi:10.1007/s13659-013-0036-5

应用天然产物 ›› 2013, Vol. 3 ›› Issue (4): 137-140.DOI: 10.1007/s13659-013-0036-5

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Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi

Timo H. J. NIEDERMEYER, Thomas JIRA, Michael LALK, Ulrike LINDEQUIST

Institute of Pharmacy, Ernst-Moritz-Arndt-University, Friedrich-Ludwig-Jahn-Straße 17, 17487 Greifswald, Germany

收稿日期:2013-04-30 修回日期:2013-06-02 出版日期:2013-08-24 发布日期:2018-02-11
通讯作者: Timo H.J.NIEDERMEYER,E-mail:timo.niedermeyer@uni-greifswald.de
基金资助:
We thank K. Weisz for recording the NMR spectra. Financial support by the federal state of MecklenburgVorpommern and the EU ("Landesforschungsschwerpunkt" EMAU 02 015 20) is gratefully acknowledged.

Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi

Timo H. J. NIEDERMEYER, Thomas JIRA, Michael LALK, Ulrike LINDEQUIST

Institute of Pharmacy, Ernst-Moritz-Arndt-University, Friedrich-Ludwig-Jahn-Straße 17, 17487 Greifswald, Germany

Received:2013-04-30 Revised:2013-06-02 Online:2013-08-24 Published:2018-02-11
Supported by:
We thank K. Weisz for recording the NMR spectra. Financial support by the federal state of MecklenburgVorpommern and the EU ("Landesforschungsschwerpunkt" EMAU 02 015 20) is gratefully acknowledged.

摘要/Abstract

摘要： Two farnesylhydroquinones were isolated from the fruiting bodies of Ganoderma pfeifferi, farnesylhydroquinone (1) and the new compound ganomycin K (2), (5S)-3-[(E)-7,8-dihydroxy-4,8-dimethylnon-3-enyl]-5-(2,5-dihydroxyphenyl)-furan-2(5H)-one. The structures of 1 and 2 were determined on the basis of mass spectrometric and NMR spectroscopic evidence. The antibacterial activity of the isolated compounds was neglectable.

关键词: Ganoderma pfeifferi, farnesylhydroquinone, ganomycin

Abstract: Two farnesylhydroquinones were isolated from the fruiting bodies of Ganoderma pfeifferi, farnesylhydroquinone (1) and the new compound ganomycin K (2), (5S)-3-[(E)-7,8-dihydroxy-4,8-dimethylnon-3-enyl]-5-(2,5-dihydroxyphenyl)-furan-2(5H)-one. The structures of 1 and 2 were determined on the basis of mass spectrometric and NMR spectroscopic evidence. The antibacterial activity of the isolated compounds was neglectable.

Key words: Ganoderma pfeifferi, farnesylhydroquinone, ganomycin

Timo H. J. NIEDERMEYER, Thomas JIRA, Michael LALK, Ulrike LINDEQUIST. Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi[J]. 应用天然产物, 2013, 3(4): 137-140.

Timo H. J. NIEDERMEYER, Thomas JIRA, Michael LALK, Ulrike LINDEQUIST. Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi[J]. Natural Products and Bioprospecting, 2013, 3(4): 137-140.

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Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi

Isolation of farnesylhydroquinones from the basidiomycete Ganoderma pfeifferi

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