Betanidin significantly reduces blood glucose levels in BALB/c mice fed with an atherogenic diet

doi:10.1007/s13659-012-0034-z

应用天然产物 ›› 2012, Vol. 2 ›› Issue (4): 154-155.DOI: 10.1007/s13659-012-0034-z

• Short Communication • 上一篇下一篇

Betanidin significantly reduces blood glucose levels in BALB/c mice fed with an atherogenic diet

Agustin LUGO-RADILLO^a,b, Ivan DELGADO-ENCISO^b, Elpidio PEÑA-BELTRÁN^c

a Instituto Nacional de Geriatría, Periférico Sur 2767, San Jerónimo Lídice, Magdalena Contreras, 10200 México D. F., México;
b Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Colonia Las Víboras, 28040 Colima, Colima, México;
c Facultad de Ciencias Biológicas y Agropecuarias, Universidad de Colima. Carr. Colima-Manzanillo km 40, 28100 Tecomán, Colima, México

收稿日期:2012-05-09 修回日期:2012-06-15 出版日期:2012-08-24 发布日期:2018-02-11
通讯作者: Agustin LUGO-RADILLO,E-mail:alugor@hotmail.com

Betanidin significantly reduces blood glucose levels in BALB/c mice fed with an atherogenic diet

Agustin LUGO-RADILLO^a,b, Ivan DELGADO-ENCISO^b, Elpidio PEÑA-BELTRÁN^c

a Instituto Nacional de Geriatría, Periférico Sur 2767, San Jerónimo Lídice, Magdalena Contreras, 10200 México D. F., México;
b Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Colonia Las Víboras, 28040 Colima, Colima, México;
c Facultad de Ciencias Biológicas y Agropecuarias, Universidad de Colima. Carr. Colima-Manzanillo km 40, 28100 Tecomán, Colima, México

Received:2012-05-09 Revised:2012-06-15 Online:2012-08-24 Published:2018-02-11

摘要/Abstract

摘要： Six weeks BALB/c mice were fed with an atherogenic diet for 24 weeks and purified water ad libitum. An experimental group was given betanidin, orally, during the last 40 days of the experiment at a dose of 9.6 mg per mouse per day. Negative controls were fed with standard rodent chow only. Glycemia was measured at the end of the experiment, after overnight fasting. The group treated with betanidin presented a highly significant reduction of 50.94% compared to positive controls. We conclude that betanidin reduces glycemia in BALB/c mice by an unidentified mechanism.

关键词: betalains, betanidin, blood glucose, hypoglycemiant

Abstract: Six weeks BALB/c mice were fed with an atherogenic diet for 24 weeks and purified water ad libitum. An experimental group was given betanidin, orally, during the last 40 days of the experiment at a dose of 9.6 mg per mouse per day. Negative controls were fed with standard rodent chow only. Glycemia was measured at the end of the experiment, after overnight fasting. The group treated with betanidin presented a highly significant reduction of 50.94% compared to positive controls. We conclude that betanidin reduces glycemia in BALB/c mice by an unidentified mechanism.

Key words: betalains, betanidin, blood glucose, hypoglycemiant

Agustin LUGO-RADILLO, Ivan DELGADO-ENCISO, Elpidio PEÑA-BELTRÁN. Betanidin significantly reduces blood glucose levels in BALB/c mice fed with an atherogenic diet[J]. 应用天然产物, 2012, 2(4): 154-155.

Agustin LUGO-RADILLO, Ivan DELGADO-ENCISO, Elpidio PEÑA-BELTRÁN. Betanidin significantly reduces blood glucose levels in BALB/c mice fed with an atherogenic diet[J]. Natural Products and Bioprospecting, 2012, 2(4): 154-155.

Betanidin significantly reduces blood glucose levels in BALB/c mice fed with an atherogenic diet

Betanidin significantly reduces blood glucose levels in BALB/c mice fed with an atherogenic diet

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 0

编辑推荐

Metrics

本文评价