关键词: 野桐属, 红叶野桐,(+)-丁香脂素, 刺五加酮, 松脂素

Abstract: ex LH-20 and preparative RP-HPLC methods. The structures of the isolated lignans were determined on the basis of analyses of spectroscopic methods(¹H- and ¹³C-NMR spectroscopy), high-resolution electrospray ionization mass spectrometry(HR-ESI-MS), and comparison of their spectroscopic data with previously reported data. The lignans were identified as 7″,8″-threo-buddlenol D(1), buddlenol D(2), 7″,8″-threo-buddlenol C(3), buddlenol C(4),(+)-syringaresinol(5), epipinoresinol(6), pinoresinol(7), 1-acetoxyl-2e,6e-dipiperonyl-3,7-dioxabicyclo-[3,3,0]-octane(8), ciwujiatone(9), lariciresinol-4'-O-β-D-glucopyranoside(10), rel-(2α,3β)-7-O-methylcedrusin(11), and dihydrodehydrodiconiferyl-alcohol 4'-O-β-D-glucoside(12). All compounds were isolated from M. paxii for the first time. Some lignans have good pharmacological activities such as antibacterial, anti-inflammatory, anti-tumor and anti-virus. The results of this study show that the leaves of M. paxii are rich in lignans with good activity, indicating that its good medicinal value may be related to these lignans.

Key words: Mallotus, Mallotus paxii ,(+)-syringaresinol, ciwujiatone, pinoresinol