Integrative Biology Journals

Natural Products and Bioprospecting ›› 2023, Vol. 13 ›› Issue (6): 42-42.DOI: 10.1007/s13659-023-00404-0

• REVIEW • Previous Articles     Next Articles

Biological activities of gastropods secretions: snail and slug slime

Muhammad Rashad1, Simone Sampò2, Amelia Cataldi1, Susi Zara1   

  1. 1. Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Via Dei Vestini 31, 66100, Chieti, Italy;
    2. International Institution of Heliciculture of Cherasco-Lumacheria Italiana Srl, Corso Einaudi 40, 12062, Cherasco, Italy
  • Received:2023-09-19 Online:2023-12-26 Published:2023-12-24
  • Contact: Susi Zara,E-mail:susi.zara@unich.it
  • Supported by:
    This research was funded by FAR 2020, 2021 Cataldi, FAR 2020, 2021 Zara and also supported by MUR National Innovation Ecosystem—Recovery and Resilience Plan (PNRR) Italy.

Biological activities of gastropods secretions: snail and slug slime

Muhammad Rashad1, Simone Sampò2, Amelia Cataldi1, Susi Zara1   

  1. 1. Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Via Dei Vestini 31, 66100, Chieti, Italy;
    2. International Institution of Heliciculture of Cherasco-Lumacheria Italiana Srl, Corso Einaudi 40, 12062, Cherasco, Italy
  • 通讯作者: Susi Zara,E-mail:susi.zara@unich.it
  • 基金资助:
    This research was funded by FAR 2020, 2021 Cataldi, FAR 2020, 2021 Zara and also supported by MUR National Innovation Ecosystem—Recovery and Resilience Plan (PNRR) Italy.

Abstract: Gastropods, a mollusk class including slugs and snails, represent an extraordinarily diverse and ecologically significant group of organisms featuring the largest class of invertebrates. They can be classified as aquatic and terrestrial animals having coiled shells, although some species have reduced or absent shells. Their unique body structure includes a muscular foot for locomotion, a visceral mass containing essential organs, and a distinct head region with sensory organs such as tentacles and eyes. They are used to secrete a complex mixture of glycoproteins, enzymes, peptides, mucus and other bioactive compounds, namely slime, which represents a tool to allow locomotion, protection, and interaction within different habitats. The biological activities of the slime have attracted considerable interest due to their diverse and potentially valuable properties ranging from defense mechanisms to potential therapeutic applications in wound healing, antimicrobial therapy, management of inflammation, and neurological disorders. This review aims at exploring the beneficial effects of snail and slug slime focusing, in particular, on the improvement of the biological processes underlying them. Continued exploration of the intricate components of these slimy secretions promises to discover new bioactive molecules with diverse applications in various scientific and industrial fields.

Key words: Snail slime, Slug slime, Biological activities, Cruelty-free method, Gastropods

摘要: Gastropods, a mollusk class including slugs and snails, represent an extraordinarily diverse and ecologically significant group of organisms featuring the largest class of invertebrates. They can be classified as aquatic and terrestrial animals having coiled shells, although some species have reduced or absent shells. Their unique body structure includes a muscular foot for locomotion, a visceral mass containing essential organs, and a distinct head region with sensory organs such as tentacles and eyes. They are used to secrete a complex mixture of glycoproteins, enzymes, peptides, mucus and other bioactive compounds, namely slime, which represents a tool to allow locomotion, protection, and interaction within different habitats. The biological activities of the slime have attracted considerable interest due to their diverse and potentially valuable properties ranging from defense mechanisms to potential therapeutic applications in wound healing, antimicrobial therapy, management of inflammation, and neurological disorders. This review aims at exploring the beneficial effects of snail and slug slime focusing, in particular, on the improvement of the biological processes underlying them. Continued exploration of the intricate components of these slimy secretions promises to discover new bioactive molecules with diverse applications in various scientific and industrial fields.

关键词: Snail slime, Slug slime, Biological activities, Cruelty-free method, Gastropods