Integrative Biology Journals

Natural Products and Bioprospecting ›› 2012, Vol. 2 ›› Issue (5): 200-205.DOI: 10.1007/s13659-012-0060-x

• Regular Article • Previous Articles     Next Articles

Twelve new compounds from the basidiomycete Boreostereum vibrans

Jian-Hai DINGa,b,c, Tao FENGa, Zheng-Hui LIa, Liang LIb, Ji-Kai LIUa   

  1. a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
    b School of Chemical Science and Technology, Yunnan University, Kunming 650091, China;
    c Graduate University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2012-07-18 Revised:2012-09-04 Online:2018-02-11 Published:2012-10-24
  • Supported by:
    This work was financially supported by National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Science Foundation of China(30830113, U1132607).

Twelve new compounds from the basidiomycete Boreostereum vibrans

Jian-Hai DINGa,b,c, Tao FENGa, Zheng-Hui LIa, Liang LIb, Ji-Kai LIUa   

  1. a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
    b School of Chemical Science and Technology, Yunnan University, Kunming 650091, China;
    c Graduate University of Chinese Academy of Sciences, Beijing 100049, China
  • 通讯作者: Ji-Kai LIU,E-mail:jkliu@mail.kib.ac.cn
  • 基金资助:
    This work was financially supported by National Basic Research Program of China(973 Program, 2009CB522300), the National Natural Science Foundation of China(30830113, U1132607).

Abstract: Seven cadinane sesquiterpenoids, named boreovibrins A-G(1-7), three dihydrobenzofurans(8-10), and two lactones(11 and 12), together with one known compound(13), were isolated from cultures of the basidiomycete Boreostereum vibrans. The new structures were elucidated by means of spectroscopic methods. Compounds 5, 6, and 11 showed weak inhibitory activities against isozymes of 11β-hydroxysteroid dehydrogenases(11β-HSD).

Key words: cadinane, sesquiterpenoid, boreovibrin, dihydrobenzofuran, lactone, Boreostereum vibrans

摘要: Seven cadinane sesquiterpenoids, named boreovibrins A-G(1-7), three dihydrobenzofurans(8-10), and two lactones(11 and 12), together with one known compound(13), were isolated from cultures of the basidiomycete Boreostereum vibrans. The new structures were elucidated by means of spectroscopic methods. Compounds 5, 6, and 11 showed weak inhibitory activities against isozymes of 11β-hydroxysteroid dehydrogenases(11β-HSD).

关键词: cadinane, sesquiterpenoid, boreovibrin, dihydrobenzofuran, lactone, Boreostereum vibrans