Integrative Biology Journals

Natural Products and Bioprospecting ›› 2018, Vol. 8 ›› Issue (4): 245-263.DOI: 10.1007/s13659-018-0176-8

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Research of Panax spp. in Kunming Institute of Botany, CAS

Yi-Jun Qiao1,2, Jia-Huan Shang1,2, Dong Wang1, Hong-Tao Zhu1, Chong-Ren Yang1, Ying-Jun Zhang1,3   

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China;
    2 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China;
    3 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China
  • Received:2018-04-19 Revised:2018-07-02 Online:2018-08-28 Published:2018-08-24
  • Contact: Ying-Jun Zhang,zhangyj@mail.kib.ac.cn
  • Supported by:
    This work was supported by the Major Science and Technique Programs in Yunnan Province (2016ZF001-001), and the Science and Technology Planning Project of Yunnan Province (2013FC008).

Research of Panax spp. in Kunming Institute of Botany, CAS

Yi-Jun Qiao1,2, Jia-Huan Shang1,2, Dong Wang1, Hong-Tao Zhu1, Chong-Ren Yang1, Ying-Jun Zhang1,3   

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China;
    2 University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China;
    3 Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China
  • 通讯作者: Ying-Jun Zhang,zhangyj@mail.kib.ac.cn
  • 基金资助:
    This work was supported by the Major Science and Technique Programs in Yunnan Province (2016ZF001-001), and the Science and Technology Planning Project of Yunnan Province (2013FC008).

Abstract: Panax, a genus of the Araliaceae family, is an important herbal group in traditional Chinese medicine (TCM). Nine species and three varieties are included in the genus of Panax, in which nearly all species have been used for medicinal purposes. Among them, Panax notoginseng (Burk) F. H. Chen, Panax ginseng C. A. Meyer and Panax quinquefolius L. are the most representative and valuable herbs world-wide, with a long history of cultivation. As the main bioactive chemical constituents, saponins with different aglycones are the major components in various Panax spp., and their pharmacological activities are mainly reflected in the effects on blood system, cardio-and cerebro-vascular systems, nervous system, metabolism, and immune regulation. Researchers of Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS), have put many efforts into conducting the investigations on Panax species. Herein, we reviewed the research progress on Panax spp. in KIB, CAS, over the past few decades, from the aspects of history and origin, phytochemistry and pharmacological activities.

Key words: Panax spp., Phytochemistry, Pharmacological activities, Saponins

摘要: Panax, a genus of the Araliaceae family, is an important herbal group in traditional Chinese medicine (TCM). Nine species and three varieties are included in the genus of Panax, in which nearly all species have been used for medicinal purposes. Among them, Panax notoginseng (Burk) F. H. Chen, Panax ginseng C. A. Meyer and Panax quinquefolius L. are the most representative and valuable herbs world-wide, with a long history of cultivation. As the main bioactive chemical constituents, saponins with different aglycones are the major components in various Panax spp., and their pharmacological activities are mainly reflected in the effects on blood system, cardio-and cerebro-vascular systems, nervous system, metabolism, and immune regulation. Researchers of Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS), have put many efforts into conducting the investigations on Panax species. Herein, we reviewed the research progress on Panax spp. in KIB, CAS, over the past few decades, from the aspects of history and origin, phytochemistry and pharmacological activities.

关键词: Panax spp., Phytochemistry, Pharmacological activities, Saponins