整合生物学期刊网

应用天然产物 ›› 2014, Vol. 4 ›› Issue (6): 315-318.DOI: 10.1007/s13659-014-0043-1

• Original article •    下一篇

Two New Steroidal Saponins from Ypsilandra thibetica

Yong-Ai Si1,2, Huan Yan1, Wei Ni1, Zhen-Hua Liu1,2, Ting-Xiang Lu1, Chang-Xiang Cheng1, Hai-Yang Liu1   

  1. 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
    2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China
  • 收稿日期:2014-09-03 修回日期:2014-10-25 出版日期:2014-12-24 发布日期:2018-02-11
  • 通讯作者: Hai-Yang Liu,e-mail:haiyangliu@mail.kib.ac.cn
  • 基金资助:
    This work was financially supported by the National Natural Science Funding of China(No. 31170333) and the Natural Science Foundation of Yunnan Province(No. 2009CC019).

Two New Steroidal Saponins from Ypsilandra thibetica

Yong-Ai Si1,2, Huan Yan1, Wei Ni1, Zhen-Hua Liu1,2, Ting-Xiang Lu1, Chang-Xiang Cheng1, Hai-Yang Liu1   

  1. 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
    2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China
  • Received:2014-09-03 Revised:2014-10-25 Online:2014-12-24 Published:2018-02-11
  • Supported by:
    This work was financially supported by the National Natural Science Funding of China(No. 31170333) and the Natural Science Foundation of Yunnan Province(No. 2009CC019).

PDF (PC)

10305

摘要： Two new monosaccharide steroidal saponins, named ypsilandroside S(1) and ypsilandroside T(2), have been isolated from the whole plants of Ypsilandra thibetica. Their structures were elucidated as heloniogenin 3-O-β-D-apiofuranoside(1) and pregna 5, 16-dien-3β, 12α-diol-20-one-3-O-β-D-apiofuranoside(2) by spectroscopic techniques(1D and 2D NMR, MS). Compounds 1 and 2 were tested for their inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells.

关键词: Ypsilandra thibetica, Liliaceae, Ypsilandroside S, Ypsilandroside T

Abstract: Two new monosaccharide steroidal saponins, named ypsilandroside S(1) and ypsilandroside T(2), have been isolated from the whole plants of Ypsilandra thibetica. Their structures were elucidated as heloniogenin 3-O-β-D-apiofuranoside(1) and pregna 5, 16-dien-3β, 12α-diol-20-one-3-O-β-D-apiofuranoside(2) by spectroscopic techniques(1D and 2D NMR, MS). Compounds 1 and 2 were tested for their inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells.

Key words: Ypsilandra thibetica, Liliaceae, Ypsilandroside S, Ypsilandroside T

版权所有 © 《应用天然产物》编辑部
地址：132# Lanhei Road, Heilongtan, Kunming 650201, Yunnan, China　
电话：0871-65223223　
E-mail：npb@mail.kib.ac.cn
技术支持：北京玛格泰克科技发展有限公司