Ten new aurovertins from cultures of the basidiomycete Albatrellus confluens

doi:10.1007/s13659-012-0088-y

应用天然产物 ›› 2013, Vol. 3 ›› Issue (1): 8-13.DOI: 10.1007/s13659-012-0088-y

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Ten new aurovertins from cultures of the basidiomycete Albatrellus confluens

Hua GUO^a,b,c, Tao FENG^a, Zheng-Hui LI^a, Ji-Kai LIU^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b School of Chemistry and Life Science, Anshan Normal College, Anshan 114005, China;
c University of Chinese Academy of Sciences, Beijing 100049, China

收稿日期:2012-10-31 修回日期:2012-12-25 出版日期:2013-02-24 发布日期:2018-02-11
通讯作者: Ji-Kai LIU,E-mail:jkliu@mail.kib.ac.cn
基金资助:
This work was financially supported by National Basic Research Program of China (973 Program, 2009CB522300), the National Natural Science Foundation of China (U1132607).

Ten new aurovertins from cultures of the basidiomycete Albatrellus confluens

Hua GUO^a,b,c, Tao FENG^a, Zheng-Hui LI^a, Ji-Kai LIU^a

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
b School of Chemistry and Life Science, Anshan Normal College, Anshan 114005, China;
c University of Chinese Academy of Sciences, Beijing 100049, China

Received:2012-10-31 Revised:2012-12-25 Online:2013-02-24 Published:2018-02-11
Supported by:
This work was financially supported by National Basic Research Program of China (973 Program, 2009CB522300), the National Natural Science Foundation of China (U1132607).

摘要/Abstract

摘要： Aurovertins J-S (1-10), together with four known metabolites, aurovertins B, C, E, and I (11-14), were isolated from cultures of the basidiomycete Albatrellus confluens. The structures of compounds 1-10 were elucidated on the basis of extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities on five tumor cell lines.

关键词: Albatrellus confluens, aurovertins, cytotoxic activities

Abstract: Aurovertins J-S (1-10), together with four known metabolites, aurovertins B, C, E, and I (11-14), were isolated from cultures of the basidiomycete Albatrellus confluens. The structures of compounds 1-10 were elucidated on the basis of extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities on five tumor cell lines.

Key words: Albatrellus confluens, aurovertins, cytotoxic activities

Hua GUO, Tao FENG, Zheng-Hui LI, Ji-Kai LIU. Ten new aurovertins from cultures of the basidiomycete Albatrellus confluens[J]. 应用天然产物, 2013, 3(1): 8-13.

Hua GUO, Tao FENG, Zheng-Hui LI, Ji-Kai LIU. Ten new aurovertins from cultures of the basidiomycete Albatrellus confluens[J]. Natural Products and Bioprospecting, 2013, 3(1): 8-13.

参考文献

[1] Baldwin, C. L.; Weaver, L. C.; Brooker, R. M.; Jacobsen, T. N.; Osborne, C. E.; Jr., Nash, H. A. Lloydia 1964, 27, 88-95.
[2] Lardy, H. A.; Connelly, J. L.; Johnson, D. Biochemistry 1964, 3, 1961-1968.
[3] Roberton, A. M.; Beechey, R. B.; Holloway, C. T.; Knight, I. G. Biochem. J. 1967, 104, 54C-55C.
[4] Ebel, R. E.; Lardy, H. A. J. Biol. Chem. 1975, 250, 4992-4995.
[5] Steyn, P. S.; Vleggaar, R.; Wessels, P. L. J. Chem. Soc., Perkin Trans. 1981, 1, 1298-1308.
[6] Van Raaij, M. J.; Abrahams, J. P.; Leslie, A. G. W.; Walker, J. E. Proc. Natl. Acad. Sci. 1996, 93, 6913-6917.
[7] Huang, T. C.; Chang, H. Y.; Hsu, C. H.; Kuo,W. H.; Chang, K. J.; Juan, H. F. J. Proteome Res. 2008, 7, 1433-1444.
[8] Wang, F.; Luo, D. Q.; Liu, J. K. J. Antibiot. 2005, 58, 412-415.
[9] Azumi, M.; Ishidoh, K. I.; Kinoshita, H.; Nihira, T.; Ihara, F.; Fujita, T.; Igarashi, Y. J. Nat. Prod. 2008, 71, 278-280.
[10] Niu, X. M.; Wang, Y. L.; Chu, Y. S.; Xue, H. X.; Li, N.; Wei, L. X.; Mo, M. H.; Zhang, K. Q. J. Agric. Food Chem. 2010, 58, 828-834.
[11] Nishiyama, S.; Toshima, H.; Kanai, H.; Yamamura, S. Tetrahedron Lett. 1986, 27, 3643-3646.
[12] Nishiyama, S.; Toshima, H.; Kanai, H.; Yamamura, S. Tetrahedron 1988, 44, 6315-6324.
[13] Steyn, P. S.; Vleggaar, R.; Wessels, P. L. J. Chem. Soc., Chem. Commun. 1979, 1041-1042.
[14] Ding, Z. H.; Dong, Z. J.; Liu, J. K. Helv. Chim. Acta 2001, 84, 259-262.
[15] Yang, W. M.; Liu, J. K.; Chen, Q.; Liu, Y. D.; Ding, Z. H.; Shen, Z. Q.; Chen, Z. H. Planta Med. 2003, 69, 715-719.
[16] Hellwig, V.; Nopper, R.; Mauler, F.; Freitag, J.; Liu, J. K.; Ding, Z. H.; Stadler, M. Arch. Pharm. 2003, 336, 119-126.
[17] Chen, Q.; Liu, M. H.; Yangl, W. M.; Zhang, Y. L.; Wang, L.; Liu, J. K. Planta Med. 2004, 70, 792-796.
[18] Ye, M.; Liu, J. K.; Lu, Z. X.; Zhao, Y.; Liu, S. F.; Li, L. L.; Tan, M.; Weng, X. X.; Li, W.; Cao, Y. FEBS Lett. 2005, 579, 3437-3443.
[19] Ye, M.; Luo, X. J.; Li, L. L.; Shi, Y.; Tan, M.; Weng, X. X.; Li, W.; Liu, J. K.; Cao, Y. Cancer Lett. 2007, 258, 199-207.
[20] Liu, Q. Y.; Shu, X. L.; Sun, A.; Sun, Q. L.; Zhang, C. X.; An, H. Z.; Liu, J. K.; Cao, X. T. Int. Immunopharmacol. 2008, 8, 1103-1111.
[21] Liu, Q. Y.; Shu, X. L.; Wang, L.; Sun, A.; Liu, J. K.; Cao, X. T. Cell. Mol. Immunol. 2008, 5, 271-278.
[22] Zhou, Z. Y.; Liu, R.; Jiang, M. Y.; Zhang, L.; Niu, Y.; Zhu, Y. C.; Dong, Z. J.; Liu, J. K. Chem. Pharm. Bull. 2009, 57, 975-978.
[23] Luo, X. J.; Li, W.; Yang, L. F.; Yu, X. F.; Xiao, L. B.; Tang, M.; Dong, X.; Deng, Q. P.; Bode, A. M.; Liu, J. K.; Cao, Y. Eur. J. Pharmacol. 2011, 670, 427-434.
[24] Zhang, H. W.; Zhang, J.; Hu, S.; Zhang, Z. J.; Zhu, C. J.; Ng, S. W.; Tan, R. X. Planta Med. 2010, 76, 1616-1621.
[25] Jiang, R. W.; Ye, W. C.; Shaw, P. C.; But, P. P. H.; Mak, T. C. W. J. Mol. Struct. 2010, 966, 18-22.
[26] Mosmann, T. J. Immunol. Methods 1983, 65, 55-63.
[27] Reed, L. J.; Muench, H. Am. J. Hygiene 1938, 27, 493-497.

Ten new aurovertins from cultures of the basidiomycete Albatrellus confluens

Ten new aurovertins from cultures of the basidiomycete Albatrellus confluens

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