Meroterpenoids from Ganoderma Species: A Review of Last Five Years

doi:10.1007/s13659-018-0164-z

应用天然产物 ›› 2018, Vol. 8 ›› Issue (3): 137-149.DOI: 10.1007/s13659-018-0164-z

• • 下一篇

Meroterpenoids from Ganoderma Species: A Review of Last Five Years

Xingrong Peng¹, Minghua Qiu^1,2

1 State Key Laboratory of Phytochemistry and Plant Sources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2 University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China

收稿日期:2018-04-10 修回日期:2018-04-23 出版日期:2018-06-24 发布日期:2018-06-06
通讯作者: Minghua Qiu
基金资助:
The research work was financially supported by the National Natural Science Foundation of China (No. 21702209 and No. 81172940), as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China (P2010-ZZ14).

Meroterpenoids from Ganoderma Species: A Review of Last Five Years

Xingrong Peng¹, Minghua Qiu^1,2

1 State Key Laboratory of Phytochemistry and Plant Sources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China;
2 University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China

Received:2018-04-10 Revised:2018-04-23 Online:2018-06-24 Published:2018-06-06
Contact: Minghua Qiu
Supported by:
The research work was financially supported by the National Natural Science Foundation of China (No. 21702209 and No. 81172940), as well as Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China (P2010-ZZ14).

摘要/Abstract

摘要： Meroterpenoids are hybrid natural products that partially originate from the terpenoid pathway. Ganoderma meroterpenoids (GMs) are a type of meroterpenoids containing a 1,2,4-trisubstituted phenyl and a polyunsaturated terpenoid part. Over last 5 years, great efforts have been made to conduct phytochemistry research on the genus Ganoderma, which have led to the isolation and identification of a number of GMs. These newly reported GMs showed diverse structures and a wide range of biological activities. This review gives an overview of new GMs from genus Ganoderma and their biological activities and biosynthetic pathway, focusing on the period from 2013 until 2018.

关键词: Ganoderma, Ganoderma meroterpenoids, New structures, Biological activities

Abstract: Meroterpenoids are hybrid natural products that partially originate from the terpenoid pathway. Ganoderma meroterpenoids (GMs) are a type of meroterpenoids containing a 1,2,4-trisubstituted phenyl and a polyunsaturated terpenoid part. Over last 5 years, great efforts have been made to conduct phytochemistry research on the genus Ganoderma, which have led to the isolation and identification of a number of GMs. These newly reported GMs showed diverse structures and a wide range of biological activities. This review gives an overview of new GMs from genus Ganoderma and their biological activities and biosynthetic pathway, focusing on the period from 2013 until 2018.

Key words: Ganoderma, Ganoderma meroterpenoids, New structures, Biological activities

Xingrong Peng, Minghua Qiu. Meroterpenoids from Ganoderma Species: A Review of Last Five Years[J]. 应用天然产物, 2018, 8(3): 137-149.

Xingrong Peng, Minghua Qiu. Meroterpenoids from Ganoderma Species: A Review of Last Five Years[J]. Natural Products and Bioprospecting, 2018, 8(3): 137-149.

参考文献

1. M. Upadhyay, B. Shrivastava, A. Jain, M. Kidwai, S. Kumar, J. Gomes, D. Goswami, A. Panda, R. Kuhad, Ann. Microbiol. 64, 839-846 (2014)
2. Y. Li, Z. Zhu, W. Yao, R. Chen, Med. Plant 3, 75-81 (2012)
3. S. Lee, S.H. Shim, J.S. Kim, K.H. Shin, S.S. Kang, Biol. Pharm. Bull. 28, 1103-1105 (2005)
4. P.H.K. Ngai, T.B. Ng, Biochem. Biophys. Res. Commun. 314, 988-993 (2004)
5. S. Gurunathan, J. Raman, S.N.A. Malek, P.A. John, S. Vikineswary, Int. J. Nanomed. 8, 4399-4413 (2013)
6. G.M. Cragg, D.J. Newman, K.M. Snader, J. Nat. Prod. 60, 52-60 (1997)
7. D.J. Newman, G.M. Cragg, K.M. Snader, Nat. Prod. Rep. 17, 215-234 (2000)
8. D.J. Newman, G.M. Cragg, K.M. Snader, J. Nat. Prod. 66, 1022-1037 (2003)
9. M.S. Butler, J. Nat. Prod. 67, 2141-2153 (2004)
10. I. Paterson, E.A. Anderson, Science 310, 451-453 (2005)
11. D.J. Newman, G.M. Cragg, J. Nat. Prod. 70, 461-477 (2007)
12. R.A.A. Mothana, R. Jansen, W.D. Julich, U. Lindequist, J. Nat. Prod. 63, 416-418 (2000)
13. X.Q. Chen, L.X. Chen, S.P. Li, J. Zhao, Phytochem. Lett. 22, 214-218 (2017)
14. M. Wang, F. Wang, F. Xu, Bioorg. Med. Chem. Lett. 26, 3342-3345 (2016)
15. X.R. Peng, J.Q. Liu, C.F. Wang, Z.H. Han, Y. Shu, X.Y. Li, L. Zhou, M.H. Qiu, Food Chem. 171, 251-257 (2015)
16. X.R. Peng, L. Li, X. Wang, G.L. Zhu, L. Zhou, M.H. Qiu, Fitoterapia 111, 18-23 (2016)
17. Q. Luo, L. Di, W.F. Dai, Q. Lu, Y.M. Yan, Z.L. Yang, R.T. Li, Y.X. Cheng, Org. Lett. 17, 1110-1113 (2015)
18. Q. Luo, L. Di, X.H. Yang, Y.X. Cheng, RSC Adv. 6, 45963-45967 (2016)
19. S.Z. Huang, B.H. Cheng, Q.Y. Ma, Q. Wang, F.D. Kong, H.F. Dai, S.Q. Qiu, P.Y. Zheng, Z.Q. Liu, Y.X. Zhao, RSC. Adv. 6, 21139-21147 (2016)
20. X.R. Peng, J.Q. Liu, Z.H. Han, X.X. Yuan, H.R. Luo, M.H. Qiu, Food Chem. 141, 920-926 (2013)
21. X.M. Niu, S.H. Li, H.D. Sun, C.T. Che, J. Nat. Prod. 69, 1364-1365 (2006)
22. J.J. Zhang, K. Ma, H.Y. Chen, K. Wang, W.P. Xiong, L. Bao, H.W. Liu, J. Antibiot. 70, 915-917 (2017)
23. K.S. Gautam, V.B. Birman, Org. Lett. 18, 1499-1501 (2016)
24. X.Y. Li, X.Y. Liu, X.Z. Jiao, H.G. Yang, Y.Y. Yao, P. Xie, Org. Lett. 18, 1944-1946 (2016)
25. D. Chen, H.M. Liu, M.M. Li, Y.M. Yan, W.D. Xu, X.N. Li, Y.X. Cheng, Chem. Commun. 51, 14594-14596 (2015)
26. H.X. Liu, L.Q. Hou, B. Yang, Y.F. Yuan, W.M. Zhang, Z.F. Xu, S.X. Qiu, H.B. Tan, Org. Lett. 19, 4786-4789 (2017)
27. X. Liu, R.D. Chen, D. Xie, J.H. Li, R.S. Wang, J.G. Dai, Yaoxue Xuebao 48, 161-169 (2013)
28. J. Gao, Y. Zeng, S. Lu, Zhiwu Xuebao (Beijing, China) 45, 751-759 (2010)
29. D. Liu, J. Gong, W. Dai, X. Kang, Z. Huang, H.M. Zhang, W. Liu, L. Liu, J. Ma, Z. Xia, Y. Chen, Y. Chen, D. Wang, P. Ni, A.Y. Guo, X. Xiong, PLoS ONE 7, e36146 (2012)
30. X.R. Peng, X. Wang, L. Chen, H. Yang, L. Lei, S.Y. Lu, L. Zhou, M.H. Qiu, Fitoterapia (2018). https://doi.org/10.1016/j.fitote.2018.03.005
31. Q. Luo, X.L. Wang, L. Di, Y.M. Yan, Q. Lu, X.H. Yang, D.B. Hu, Y.X. Cheng, Tetrahedron 71, 840-845 (2015)
32. Q. Luo, X.H. Yang, Z.L. Yang, Z.C. Tu, Y.X. Cheng, Tetrahedron 30, 4564-4574 (2016)
33. K. Wang, L. Bao, K. Ma, J.J. Zhang, B.S. Chen, J.J. Han, J.W. Ren, H.J. Luo, H.W. Liu, Eur. J. Med. Chem. 127, 1035-1046 (2017)
34. M. Dou, R.T. Li, Y.X. Chen, Chin. Herb. Med. 8, 85-88 (2016)
35. B.S. Chen, J. Tian, J.J. Zhang, K. Wang, L. Liu, B. Yang, L. Bao, H.W. Liu, Fitoterapia 120, 6-16 (2017)
36. X.F. Wang, Y.M. Yan, X.L. Wang, X.J. Ma, X.Y. Fu, Y.X. Cheng, J. Asian Nat. Prod. Res. 17, 329-332 (2015)
37. W.W. Cao, Q. Luo, Y.X. Chen, S.M. Wang, Fitoterapia 110, 110-115 (2016)
38. Y.M. Yan, X.L. Wang, Q. Luo, L.P. Jiang, C.P. Yang, B. Hou, Z.L. Zuo, Y.B. Chen, Y.X. Cheng, Phytochemistry 114, 155-162 (2015)
39. F.J. Zhou, X.L. Wang, S.M. Wang, Y.X. Cheng, Nat. Prod. Res. Dev. 27, 22-25 (2015)
40. Q. Luo, Z.C. Tu, Z.L. Yang, Y.X. Cheng, Fitoterapia 125, 273-280 (2018)
41. Q.L. Gao, P.X. Guo, Q. Luo, H. Yan, Y.X. Cheng, Nat. Prod. Commun. 10, 2019-2022 (2015)
42. Q. Luo, X.Y. Wei, J. Yang, J.F. Luo, R. Liang, Z.C. Tu, Y.X. Cheng, J. Nat. Prod. 80, 61-70 (2017)
43. Y.M. Yan, X.L. Wang, L.L. Zhou, F.J. Zhou, R. Li, Y. Tian, Z.L. Zuo, P. Fang, A.C.K. Chung, F.F. Hou, Y.X. Cheng, J. Ethnopharm. 176, 385-393 (2015)
44. Y.M. Yan, J. Ai, L.L. Zhou, A.C.K. Chung, R. Li, J. Nie, P. Fang, X.L. Wang, J. Luo, Q. Hu, F.F. Hou, Y.X. Cheng, Org. Lett. 15, 5488-5491 (2013)
45. X.R. Peng, J.Q. Liu, L.S. Wan, X.N. Li, Y.Y. Yan, M.H. Qiu, Org. Lett. 16, 5262-5265 (2014)
46. M. Dou, L. Di, L.L. Zhou, Y.M. Yan, X.L. Wang, F.J. Zhou, Z.L. Yang, R.T. Li, F.F. Hou, Y.X. Cheng, Org. Lett. 16, 6064-6067 (2014)
47. Q. Luo, L. Tian, L. Di, Y.M. Yan, X.Y. Wei, X.F. Wang, Y.X. Cheng, Org. Lett. 17, 1565-1568 (2015)
48. L. Li, H. Li, X.R. Peng, B. Hou, M.Y. Yu, J.R. Dong, X.N. Li, L. Zhou, J. Yang, M.H. Qiu, Org. Lett. 18, 6078-6081 (2016)
49. F.J. Zhou, Y. Nian, Y.M. Yan, Y. Gong, Q. Luo, Y. Zhang, B. Hou, Z.L. Zuo, S.M. Wang, H.H. Jiang, J. Yang, Y.X. Cheng, Org. Lett. 17, 3082-3085 (2015)
50. H.P. Chen, Z.Z. Zhao, Y. Zhang, X. Bai, L. Zhang, J.K. Liu, RSC Adv. 6, 64469-64473 (2016)
51. X.L. Wang, F.J. Zhou, M. Dou, Y.M. Yan, S.M. Wang, L. Di, Y.X. Cheng, Bioorg. Med. Chem. Lett. 26, 5507-5512 (2016)

[1]	Zhou-Wei Wu, Xue-Fang Zhao, Chen-Xi Quan, Xiao-Cui Liu, Xin-Yu Tao, Yu-jie Li, Xing-Rong Peng, Ming-Hua Qiu. Structure-function insights of natural Ganoderma polysaccharides: advances in biosynthesis and functional food applications[J]. 应用天然产物, 2025, 15(2): 15-15.
[2]	Jin-Ning Chu, Premanand Krishnan, Kuan-Hon Lim. A comprehensive review on the chemical constituents, sesquiterpenoid biosynthesis and biological activities of Sarcandra glabra[J]. 应用天然产物, 2023, 13(6): 53-53.
[3]	Muhammad Rashad, Simone Sampò, Amelia Cataldi, Susi Zara. Biological activities of gastropods secretions: snail and slug slime[J]. 应用天然产物, 2023, 13(6): 42-42.
[4]	Jin-Tao Ma, Da-Wei Li, Ji-Kai Liu, Juan He. Advances in Research on Chemical Constituents and Their Biological Activities of the Genus Actinidia[J]. 应用天然产物, 2021, 11(6): 573-609.
[5]	Li-Wen Tian, Zhen Zhang, Hai-Lan Long, Ying-Jun Zhang. Steroidal Saponins from the Genus Smilax and Their Biological Activities[J]. 应用天然产物, 2017, 7(4): 283-298.
[6]	Fidele Ntie-Kang, Leonel E. Njume, Yvette I. Malange, Stefan Günther, Wolfgang Sippl, Joseph N. Yong. The Chemistry and Biological Activities of Natural Products from Northern African Plant Families: From Taccaceae to Zygophyllaceae[J]. 应用天然产物, 2016, 6(2): 63-96.
[7]	Ming-Ming Zhai, Jie Li, Chun-Xiao Jiang, Yan-Ping Shi, Duo-Long Di, Phillip Crews, Quan-Xiang Wu. The Bioactive Secondary Metabolites from Talaromyces species[J]. 应用天然产物, 2016, 6(1): 1-24.

Meroterpenoids from Ganoderma Species: A Review of Last Five Years

Meroterpenoids from Ganoderma Species: A Review of Last Five Years

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 7

编辑推荐

Metrics

本文评价