Integrative Biology Journals

Plant Diversity ›› 2005, Vol. 27 ›› Issue (06): 691-694.

• Articles • Previous Articles     Next Articles

Chemical Constituents of Tibetan Herbal Medicine Saxifraga melanocentra

ZUO Guo-Ying1 , 2 , ZHANG Zhi-Jun1 , CHEN Li-Rong1 , XU Xiao-Jie1   

  1. 1 College of Chemistry and Molecular Engineering , Peking University , Beijing 100871 , China; 2 Kunming Genernal Hospital , Kunming 650032 , China
  • Received:2005-04-07 Online:2005-10-25 Published:2005-10-25
  • Contact: XU Xiao-Jie

藏药黑蕊虎耳草的化学成分

左国营1,2, 张志军1 , 陈丽蓉1 , 徐筱杰1   

  1. 1 北京大学化学与分子工程学院; 2 成都军区昆明总医院
  • 通讯作者: 徐筱杰

Abstract: From the aerial parts of Saxifraga melanocentra, ten compounds were isolated and identified with spectral analysis and compared with authentic samples as kaermpferol ( 1 ) , quercetin ( 2 ) , kaempferol-3- O-β-D-glucoside ( 3 ) , quercetin-3- O-β-D-glucoside ( 4 ) , kaempferol-3-rutinoside ( 5 ) ,
rutin (6) , 2″- O-galloylrutin (7 ) , bergenin ( 8 ) , gallic acid ( 9) and methyl gallate ( 10) . Six compounds were found from the plant for the first time with the exception of 2 , 6 , 8 and 10 . These results provided new chemical evidences for the bioactive investigation of this plant .

Key words: Saxifraga melanocentra

摘要: 从黑蕊虎耳草(Saxifraga melanocentra) 地上部分的乙醇提取物中分离得到10 个化合物, 通过波谱分析并与有关对照品比较, 将其结构鉴定为山奈酚( 1) , 槲皮素(2 ) , 山奈酚-3-O-β-D-葡萄糖苷(黄芪苷) ( 3) , 槲皮素-3- O-β-D-葡萄糖苷(4 ) , 山奈酚-3- O-芦丁糖苷(5) , 芦丁(6 ) , 2″- O-没食子酰芦丁(7 ) , 岩白菜素( 8 ) , 没食子酸( 9) 和没食子酸甲酯(10) , 除化合物2、6、8 和10 外, 其余6 个化合物均为首次从虎耳草属植物中得到。这些成分的鉴定为该植物的药效学研究提供了新的化学依据。

关键词: 黑蕊虎耳草, 黄酮, 岩白菜素FONT