Abstract: Doliroside A, a main saponin was isolated from the roots of Dolichos falcata Klein., a folk medicine in South China, which was suggested as medi- cagenic acid 23-monomethylate- 3-O-β-D-glucopyranoside (2 ) by means of 13sC NMR, MS and chemical degredation.

Key words: doliroside, triterperoid, saponin

摘要： 大麻药即镰叶山扁豆(Dolichos falcata Klein),为豆科山扁豆属植物,产我国南部,民间以根火药,有止血、镇痛、止咳平喘之效。田成国等报道大麻药根的醇提取物对肿瘤细胞有抑制作用,临床可缓解子宫颈癌,并从其皂甙部分水解得到苜蓿酸(medicagenc acid);黄厚聘等报道大麻药总皂甙有较强的利尿作用,毒性小最近报道大麻药总皂甙对小鼠S37移植性肿瘤有抑制活性。由于皂甙是大麻药的活性成分,我们对其进行了研究,本文报告大麻药甙A(doliroside A)的化学结构。

关键词: 大麻药, 三萜皂甙成分